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Open Access

Peer-reviewed

Research Article

Chaetocin induces apoptosis in human melanoma cells through the generation of reactive oxygen species and the intrinsic mitochondrial pathway, and exerts its anti-tumor activity in vivo

Xinming Han,

Affiliations Department of Plastic and Reconstructive Surgery, Chinese PLA General Hospital, Beijing, China, Medical Cosmetic Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
⨯
Yan Han ,

* E-mail: han8yan@sina.com

Affiliation Department of Plastic and Reconstructive Surgery, Chinese PLA General Hospital, Beijing, China
⨯
Yongsheng Zheng,

Affiliation Medical Cosmetic Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
⨯
Qiang Sun,

Affiliation Medical Cosmetic Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
⨯
Tao Ma,

Affiliation Medical Cosmetic Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
⨯
Junyi Zhang,

Affiliation Medical Cosmetic Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
⨯
Lianji Xu

Affiliation Medical Cosmetic Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
⨯

Chaetocin induces apoptosis in human melanoma cells through the generation of reactive oxygen species and the intrinsic mitochondrial pathway, and exerts its anti-tumor activity in vivo

Xinming Han,
Yan Han,
Yongsheng Zheng,
Qiang Sun,
Tao Ma,
Junyi Zhang,
Lianji Xu

x

Published: April 18, 2017
https://doi.org/10.1371/journal.pone.0175950

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Mouse models
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Melanoma
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