Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo

Irina N. Baranova; Ana C. P. Souza; Alexander V. Bocharov; Tatyana G. Vishnyakova; Xuzhen Hu; Boris L. Vaisman; Marcelo J. Amar; Zhigang Chen; Alan T. Remaley; Amy P. Patterson; Peter S. T. Yuen; Robert A. Star; Thomas L. Eggerman

doi:10.1371/journal.pone.0175824

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Open Access

Peer-reviewed

Research Article

Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo

Irina N. Baranova ,

* E-mail: ibaranova@mail.nih.gov

Affiliation Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America

http://orcid.org/0000-0003-4250-1340

⨯
Ana C. P. Souza,

Affiliation Renal Diagnostics and Therapeutics Unit, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Alexander V. Bocharov,

Affiliation Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Tatyana G. Vishnyakova,

Affiliation Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Xuzhen Hu,

Affiliation Renal Diagnostics and Therapeutics Unit, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Boris L. Vaisman,

Affiliation National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Marcelo J. Amar,

Affiliation National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Zhigang Chen,

Affiliation Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Alan T. Remaley,

Affiliation National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Amy P. Patterson,

Affiliations Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Peter S. T. Yuen,

Affiliation Renal Diagnostics and Therapeutics Unit, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Robert A. Star,

Affiliation Renal Diagnostics and Therapeutics Unit, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Thomas L. Eggerman

Affiliations Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America, Division of Diabetes, Endocrinology and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo

Irina N. Baranova,
Ana C. P. Souza,
Alexander V. Bocharov,
Tatyana G. Vishnyakova,
Xuzhen Hu,
Boris L. Vaisman,
Marcelo J. Amar,
Zhigang Chen,
Alan T. Remaley,
Amy P. Patterson

Published: April 19, 2017
https://doi.org/10.1371/journal.pone.0175824

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