An activity-integrated strategy of the identification, screening and determination of potential neuraminidase inhibitors from Radix Scutellariae

Wei Liu; Huilin Wang; Bo Zhu; Chengqian Yin; Shuyang Chen; Jin Li; Xie-an Yu; John Teye Azietaku; Mingrui An; Xiu-mei Gao; Yan-xu Chang

doi:10.1371/journal.pone.0175751

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Open Access

Peer-reviewed

Research Article

An activity-integrated strategy of the identification, screening and determination of potential neuraminidase inhibitors from Radix Scutellariae

Wei Liu,

Affiliations Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China, Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, China
⨯
Huilin Wang,

Affiliations Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China, Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, China
⨯
Bo Zhu,

Affiliation Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Chengqian Yin,

Affiliation Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Shuyang Chen,

Affiliation Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Jin Li,

Affiliations Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China, Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, China
⨯
Xie-an Yu,

Affiliations Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China, Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, China
⨯
John Teye Azietaku,

Affiliations Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China, Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, China
⨯
Mingrui An,

Affiliation Department of Surgery, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Xiu-mei Gao ,

* E-mail: Tcmcyx@126.com (Y.-x.Chang); gaoxiumei@tjutcm.edu.cn (X-m Gao)

Affiliations Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China, Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, China
⨯
Yan-xu Chang

* E-mail: Tcmcyx@126.com (Y.-x.Chang); gaoxiumei@tjutcm.edu.cn (X-m Gao)

Affiliations Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China, Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, China
⨯

An activity-integrated strategy of the identification, screening and determination of potential neuraminidase inhibitors from Radix Scutellariae

Wei Liu,
Huilin Wang,
Bo Zhu,
Chengqian Yin,
Shuyang Chen,
Jin Li,
Xie-an Yu,
John Teye Azietaku,
Mingrui An,
Xiu-mei Gao

Published: May 9, 2017
https://doi.org/10.1371/journal.pone.0175751

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