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Open Access
Peer-reviewed
Research Article
Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease
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Chelsea Caspell-Garcia,
Affiliation Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, United States of America
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Tanya Simuni,
Affiliation Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America
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Duygu Tosun-Turgut,
Affiliation University of California, San Francisco, San Francisco, CA, United States of America
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I-Wei Wu,
Affiliation University of California, San Francisco, San Francisco, CA, United States of America
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Yu Zhang,
Affiliation University of California, San Francisco, San Francisco, CA, United States of America
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Mike Nalls,
Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States of America
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Andrew Singleton,
Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States of America
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Leslie A. Shaw,
Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America
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Ju-Hee Kang,
Affiliations Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America, Department of Pharmacology & Clinical Pharmacology, Inha University School of Medicine, Incheon, Republic of Korea
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John Q. Trojanowski,
Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America
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Andrew Siderowf,
Affiliation Avid Radiopharmaceuticals, Philadelphia, PA, United States of America
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Christopher Coffey,
Affiliation Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, United States of America
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Shirley Lasch,
Affiliation Institute for Neurodegenerative Disorders (IND) and Molecular NeuroImaging, LLC (MNI), New Haven CT, United States of America
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Dag Aarsland,
Affiliations Department of Old Age Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, England, Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway
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David Burn,
Affiliation Institute for Ageing and Health, Newcastle University, Newcastle, England
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Lana M. Chahine,
Affiliation Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America
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Alberto J. Espay,
Affiliation Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH, United States of America
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Eric D. Foster,
Affiliation Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, United States of America
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Keith A. Hawkins,
Affiliation Department of Psychiatry, Yale School of Medicine, New Haven, CT, United States of America
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Irene Litvan,
Affiliation UCSD Movement Disorder Center, Department of Neurosciences, University of California San Diego, San Diego, CA, United States of America
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Irene Richard,
Affiliation Departments of Neurology and Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States of America
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Daniel Weintraub ,
* E-mail: Daniel.Weintraub@uphs.upenn.edu
Affiliations Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America, Parkinson’s Disease Research, Education and Clinical Center (PADRECC and MIRECC), Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, United States of America, Mental Illness Research, Education and Clinical Center (MIRECC), Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, United States of America
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the Parkinson’s Progression Markers Initiative (PPMI)
¶Complete membership of the author group can be found in the acknowledgments section.
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Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease
- Chelsea Caspell-Garcia,
- Tanya Simuni,
- Duygu Tosun-Turgut,
- I-Wei Wu,
- Yu Zhang,
- Mike Nalls,
- Andrew Singleton,
- Leslie A. Shaw,
- Ju-Hee Kang,
- John Q. Trojanowski
- Published: May 17, 2017
- https://doi.org/10.1371/journal.pone.0175674