Genetic factors influencing frontostriatal dysfunction and the development of dementia in Parkinson's disease

Ismael Huertas; Silvia Jesús; Francisco Javier García-Gómez; José Antonio Lojo; Inmaculada Bernal-Bernal; Marta Bonilla-Toribio; Juan Francisco Martín-Rodriguez; David García-Solís; Pilar Gómez-Garre; Pablo Mir

doi:10.1371/journal.pone.0175560

Loading metrics

Open Access

Peer-reviewed

Research Article

Genetic factors influencing frontostriatal dysfunction and the development of dementia in Parkinson's disease

Ismael Huertas,

Affiliation Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
⨯
Silvia Jesús,

Affiliation Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
⨯
Francisco Javier García-Gómez,

Affiliation Servicio de Medicina Nuclear. UDIM. Hospital Universitario Virgen del Rocío, Seville, Spain
⨯
José Antonio Lojo,

Affiliation Servicio de Medicina Nuclear. UDIM. Hospital Universitario Virgen del Rocío, Seville, Spain
⨯
Inmaculada Bernal-Bernal,

Affiliation Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
⨯
Marta Bonilla-Toribio,

Affiliation Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
⨯
Juan Francisco Martín-Rodriguez,

Affiliation Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
⨯
David García-Solís,

Affiliations Servicio de Medicina Nuclear. UDIM. Hospital Universitario Virgen del Rocío, Seville, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain
⨯
Pilar Gómez-Garre,

Affiliations Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain
⨯
Pablo Mir

* E-mail: pmir@us.es

Affiliations Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain
⨯

Genetic factors influencing frontostriatal dysfunction and the development of dementia in Parkinson's disease

Ismael Huertas,
Silvia Jesús,
Francisco Javier García-Gómez,
José Antonio Lojo,
Inmaculada Bernal-Bernal,
Marta Bonilla-Toribio,
Juan Francisco Martín-Rodriguez,
David García-Solís,
Pilar Gómez-Garre,
Pablo Mir

Published: April 11, 2017
https://doi.org/10.1371/journal.pone.0175560

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Dementia
Is the Subject Area "Dementia" applicable to this article?

Thanks for your feedback.
Parkinson disease
Is the Subject Area "Parkinson disease" applicable to this article?

Thanks for your feedback.
Dopaminergics
Is the Subject Area "Dopaminergics" applicable to this article?

Thanks for your feedback.
Alleles
Is the Subject Area "Alleles" applicable to this article?

Thanks for your feedback.
Cognitive impairment
Is the Subject Area "Cognitive impairment" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
Genetic loci
Is the Subject Area "Genetic loci" applicable to this article?

Thanks for your feedback.
Single photon emission computed tomography
Is the Subject Area "Single photon emission computed tomography" applicable to this article?

Thanks for your feedback.