Neem leaf glycoprotein prevents post-surgical sarcoma recurrence in Swiss mice by differentially regulating cytotoxic T and myeloid-derived suppressor cells

Madhurima Sarkar; Sarbari Ghosh; Avishek Bhuniya; Tithi Ghosh; Ipsita Guha; Subhasis Barik; Jaydip Biswas; Anamika Bose; Rathindranath Baral

doi:10.1371/journal.pone.0175540

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Open Access

Peer-reviewed

Research Article

Neem leaf glycoprotein prevents post-surgical sarcoma recurrence in Swiss mice by differentially regulating cytotoxic T and myeloid-derived suppressor cells

Madhurima Sarkar,

Affiliation Department of Immunoregulation and Immunodiagnostics, Chittaranjan National Cancer Institute (CNCI), Kolkata 700026, India
⨯
Sarbari Ghosh,

Affiliation Department of Immunoregulation and Immunodiagnostics, Chittaranjan National Cancer Institute (CNCI), Kolkata 700026, India
⨯
Avishek Bhuniya,

Affiliation Department of Immunoregulation and Immunodiagnostics, Chittaranjan National Cancer Institute (CNCI), Kolkata 700026, India
⨯
Tithi Ghosh,

Affiliation Department of Immunoregulation and Immunodiagnostics, Chittaranjan National Cancer Institute (CNCI), Kolkata 700026, India
⨯
Ipsita Guha,

Affiliation Department of Immunoregulation and Immunodiagnostics, Chittaranjan National Cancer Institute (CNCI), Kolkata 700026, India
⨯
Subhasis Barik,

Affiliation Department of Immunoregulation and Immunodiagnostics, Chittaranjan National Cancer Institute (CNCI), Kolkata 700026, India
⨯
Jaydip Biswas,

Affiliation Department of Surgical Oncology and Medical Oncology, Chittaranjan National Cancer Institute (CNCI), Kolkata 700026, India
⨯
Anamika Bose ,

Contributed equally to this work with: Anamika Bose, Rathindranath Baral

Affiliation Department of Immunoregulation and Immunodiagnostics, Chittaranjan National Cancer Institute (CNCI), Kolkata 700026, India
⨯
Rathindranath Baral

Contributed equally to this work with: Anamika Bose, Rathindranath Baral

* E-mail: baralrathin@hotmail.com, rathindranath.baral@cnci.org.in

Affiliation Department of Immunoregulation and Immunodiagnostics, Chittaranjan National Cancer Institute (CNCI), Kolkata 700026, India
⨯

Neem leaf glycoprotein prevents post-surgical sarcoma recurrence in Swiss mice by differentially regulating cytotoxic T and myeloid-derived suppressor cells

Madhurima Sarkar,
Sarbari Ghosh,
Avishek Bhuniya,
Tithi Ghosh,
Ipsita Guha,
Subhasis Barik,
Jaydip Biswas,
Anamika Bose,
Rathindranath Baral

Published: April 17, 2017
https://doi.org/10.1371/journal.pone.0175540

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Cytotoxic T cells
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T cells
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Cancers and neoplasms
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Malignant tumors
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Surgical oncology
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Flow cytometry
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Sarcoma
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Cancer treatment
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