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Open Access
Peer-reviewed
Research Article
Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record
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Wei-Qi Wei ,
Contributed equally to this work with: Wei-Qi Wei, Lisa A. Bastarache
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing
Affiliation Departments of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America
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Lisa A. Bastarache ,
Contributed equally to this work with: Wei-Qi Wei, Lisa A. Bastarache
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing
Affiliation Departments of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America
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Robert J. Carroll,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Departments of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America
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Joy E. Marlo,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Departments of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America
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Travis J. Osterman,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliations Departments of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America, Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America
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Eric R. Gamazon,
Roles Conceptualization, Data curation, Methodology, Software, Visualization, Writing – review & editing
Affiliations Vanderbilt Genetic Institute and the Division of Genetic Medicine, Vanderbilt University, Nashville, TN, United States of America, Department of Clinical Epidemiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, Department of Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, Department of Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
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Nancy J. Cox,
Roles Conceptualization, Data curation, Methodology, Software, Validation, Writing – review & editing
Affiliation Vanderbilt Genetic Institute and the Division of Genetic Medicine, Vanderbilt University, Nashville, TN, United States of America
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Dan M. Roden,
Roles Conceptualization, Funding acquisition, Methodology, Resources, Writing – review & editing
Affiliations Departments of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America, Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America, Department of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, United States of America
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Joshua C. Denny
Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: josh.denny@Vanderbilt.Edu
Affiliations Departments of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America, Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America
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Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record
- Wei-Qi Wei,
- Lisa A. Bastarache,
- Robert J. Carroll,
- Joy E. Marlo,
- Travis J. Osterman,
- Eric R. Gamazon,
- Nancy J. Cox,
- Dan M. Roden,
- Joshua C. Denny
![PLOS](/resource/img/logo-plos.png)
- Published: July 7, 2017
- https://doi.org/10.1371/journal.pone.0175508