Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D2

Nanae Nagata; Hiroko Iwanari; Hidetoshi Kumagai; Osamu Kusano-Arai; Yuichi Ikeda; Kosuke Aritake; Takao Hamakubo; Yoshihiro Urade

doi:10.1371/journal.pone.0175452

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Open Access

Peer-reviewed

Research Article

Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D₂

Nanae Nagata ,

* E-mail: urade.yoshihiro.ft@u.tsukuba.ac.jp (YU); nagata.nanae.gm@u.tsukuba.ac.jp (NN)

Affiliations International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan, Department of Molecular Behavioral Biology, Osaka Bioscience Institute, Furuedai, Suita, Osaka, Japan
⨯
Hiroko Iwanari,

Affiliation Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan
⨯
Hidetoshi Kumagai,

Affiliations Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, Tokyo, Japan, Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
⨯
Osamu Kusano-Arai,

Affiliation Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan
⨯
Yuichi Ikeda,

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
⨯
Kosuke Aritake,

Affiliations International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan, Department of Molecular Behavioral Biology, Osaka Bioscience Institute, Furuedai, Suita, Osaka, Japan
⨯
Takao Hamakubo,

Affiliation Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan
⨯
Yoshihiro Urade

* E-mail: urade.yoshihiro.ft@u.tsukuba.ac.jp (YU); nagata.nanae.gm@u.tsukuba.ac.jp (NN)

Affiliations International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan, Department of Molecular Behavioral Biology, Osaka Bioscience Institute, Furuedai, Suita, Osaka, Japan
⨯

Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D₂

Nanae Nagata,
Hiroko Iwanari,
Hidetoshi Kumagai,
Osamu Kusano-Arai,
Yuichi Ikeda,
Kosuke Aritake,
Takao Hamakubo,
Yoshihiro Urade

Published: April 10, 2017
https://doi.org/10.1371/journal.pone.0175452

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