Isomalto-oligosaccharides ameliorate visceral hyperalgesia with repair damage of ileal epithelial ultrastructure in rats

Weida Wang; Haiwei Xin; Xiucai Fang; Hongtao Dou; Fangyi Liu; Dan Huang; Shaomei Han; Guijun Fei; Liming Zhu; Shenghua Zha; Hong Zhang; Meiyun Ke

doi:10.1371/journal.pone.0175276

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Open Access

Peer-reviewed

Research Article

Isomalto-oligosaccharides ameliorate visceral hyperalgesia with repair damage of ileal epithelial ultrastructure in rats

Weida Wang ,

Contributed equally to this work with: Weida Wang, Haiwei Xin

Current address: Department of Hemotology and Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou,China

Affiliation Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

http://orcid.org/0000-0002-8272-5421

⨯
Haiwei Xin ,

Contributed equally to this work with: Weida Wang, Haiwei Xin

Affiliation Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Xiucai Fang ,

* E-mail: fangxiucai2@aliyun.com

Affiliation Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Hongtao Dou,

Affiliation Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Fangyi Liu,

Affiliation Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Dan Huang,

Affiliation Department of Gastroenterology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
⨯
Shaomei Han,

Affiliation Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, China
⨯
Guijun Fei,

Affiliation Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Liming Zhu,

Affiliation Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Shenghua Zha,

Affiliation Beijing Tongrentang Health-Pharmaceutical Co., Ltd., Beijing, China
⨯
Hong Zhang,

Affiliation Beijing Tongrentang Health-Pharmaceutical Co., Ltd., Beijing, China
⨯
Meiyun Ke

Affiliation Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯

Isomalto-oligosaccharides ameliorate visceral hyperalgesia with repair damage of ileal epithelial ultrastructure in rats

Weida Wang,
Haiwei Xin,
Xiucai Fang,
Hongtao Dou,
Fangyi Liu,
Dan Huang,
Shaomei Han,
Guijun Fei,
Liming Zhu,
Shenghua Zha

Published: April 24, 2017
https://doi.org/10.1371/journal.pone.0175276

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