KChIP2 regulates the cardiac Ca2+ transient and myocyte contractility by targeting ryanodine receptor activity

Open Access

Peer-reviewed

Research Article

KChIP2 regulates the cardiac Ca²⁺ transient and myocyte contractility by targeting ryanodine receptor activity

Drew M. Nassal,

Affiliations Heart and Vascular Research Center, Department of Medicine, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, United States of America
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Xiaoping Wan,

Affiliation Heart and Vascular Research Center, Department of Medicine, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, United States of America
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Haiyan Liu,

Affiliation Heart and Vascular Research Center, Department of Medicine, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, United States of America
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Kenneth R. Laurita,

Affiliation Heart and Vascular Research Center, Department of Medicine, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, United States of America
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Isabelle Deschênes

* E-mail: isabelle.deschenes@case.edu

Affiliations Heart and Vascular Research Center, Department of Medicine, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, United States of America

http://orcid.org/0000-0002-1812-7267

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Muscle cells
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Guinea pigs
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Heart failure
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Muscle contraction
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Action potentials
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Protein expression
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Caffeine
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Sarcomeres
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