Evaluation of a modified meropenem hydrolysis assay on a large cohort of KPC and VIM carbapenemase-producing Enterobacteriaceae

Adriana Calderaro; Mirko Buttrini; Maddalena Piergianni; Sara Montecchini; Monica Martinelli; Silvia Covan; Giovanna Piccolo; Maria Cristina Medici; Maria Cristina Arcangeletti; Carlo Chezzi; Flora De Conto

doi:10.1371/journal.pone.0174908

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Open Access

Peer-reviewed

Research Article

Evaluation of a modified meropenem hydrolysis assay on a large cohort of KPC and VIM carbapenemase-producing Enterobacteriaceae

Adriana Calderaro ,

* E-mail: adriana.calderaro@unipr.it

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Mirko Buttrini,

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Maddalena Piergianni,

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Sara Montecchini,

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Monica Martinelli,

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Silvia Covan,

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Giovanna Piccolo,

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Maria Cristina Medici,

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Maria Cristina Arcangeletti,

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Carlo Chezzi,

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Flora De Conto

Affiliation Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯

Evaluation of a modified meropenem hydrolysis assay on a large cohort of KPC and VIM carbapenemase-producing Enterobacteriaceae

Adriana Calderaro,
Mirko Buttrini,
Maddalena Piergianni,
Sara Montecchini,
Monica Martinelli,
Silvia Covan,
Giovanna Piccolo,
Maria Cristina Medici,
Maria Cristina Arcangeletti,
Carlo Chezzi

Published: April 6, 2017
https://doi.org/10.1371/journal.pone.0174908

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Klebsiella pneumoniae
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Enterobacteriaceae
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Hydrolysis
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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
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Computer software
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Antibiotics
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