Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability

• Jeran K. Stratford,

  Affiliations Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0003-4305-1468

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• Feng Yan,

  Affiliation Department of Cell Biology and Physiology University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Rebecca A. Hill,

  Affiliation Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Michael B. Major,

  Affiliations Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Cell Biology and Physiology University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Lee M. Graves,

  Affiliations Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Channing J. Der,

  Affiliations Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Jen Jen Yeh

  * E-mail: jjyeh@med.unc.edu

  Affiliations Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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