Genetically engineered rat gliomas: PDGF-driven tumor initiation and progression in tv-a transgenic rats recreate key features of human brain cancer

• Nina P. Connolly,

  Affiliations Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  http://orcid.org/0000-0003-0498-6148

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• Jesse A. Stokum,

  Affiliation Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• Craig S. Schneider,

  Affiliation Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• Tatsuya Ozawa,

  Affiliation Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington, United States of America

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• Su Xu,

  Affiliation Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• Rebeca Galisteo,

  Affiliation Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• Rudolph J. Castellani,

  Affiliation Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• Anthony J. Kim,

  Affiliations Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• J. Marc Simard,

  Affiliations Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• Jeffrey A. Winkles,

  Affiliations Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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• Eric C. Holland,

  Affiliation Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington, United States of America

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• Graeme F. Woodworth

  * E-mail: gwoodworth@som.umaryland.edu

  Affiliations Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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