Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice

Patrick P. Lowe; Benedek Gyongyosi; Abhishek Satishchandran; Arvin Iracheta-Vellve; Aditya Ambade; Karen Kodys; Donna Catalano; Doyle V. Ward; Gyongyi Szabo

doi:10.1371/journal.pone.0174544

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Peer-reviewed

Research Article

Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice

Patrick P. Lowe ,

Contributed equally to this work with: Patrick P. Lowe, Benedek Gyongyosi

Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Benedek Gyongyosi ,

Contributed equally to this work with: Patrick P. Lowe, Benedek Gyongyosi

Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Abhishek Satishchandran,

Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Arvin Iracheta-Vellve,

Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Aditya Ambade,

Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Karen Kodys,

Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Donna Catalano,

Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Doyle V. Ward,

Affiliations Center for Microbiome Research, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Gyongyi Szabo

* E-mail: Gyongyi.Szabo@umassmed.edu

Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯

Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice

Patrick P. Lowe,
Benedek Gyongyosi,
Abhishek Satishchandran,
Arvin Iracheta-Vellve,
Aditya Ambade,
Karen Kodys,
Donna Catalano,
Doyle V. Ward,
Gyongyi Szabo

Published: March 28, 2017
https://doi.org/10.1371/journal.pone.0174544

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Gut bacteria
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