A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts

Sara Lindström; Stephanie Loomis; Constance Turman; Hongyan Huang; Jinyan Huang; Hugues Aschard; Andrew T. Chan; Hyon Choi; Marilyn Cornelis; Gary Curhan; Immaculata De Vivo; A. Heather Eliassen; Charles Fuchs; Michael Gaziano; Susan E. Hankinson; Frank Hu; Majken Jensen; Jae H. Kang; Christopher Kabrhel; Liming Liang; Louis R. Pasquale; Eric Rimm; Meir J. Stampfer; Rulla M. Tamimi; Shelley S. Tworoger; Janey L. Wiggs; David J. Hunter; Peter Kraft

doi:10.1371/journal.pone.0173997

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Peer-reviewed

Research Article

A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts

Sara Lindström ,

* E-mail: saralind@uw.edu

Affiliations Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, University of Washington, Seattle, WA, United States of America

http://orcid.org/0000-0002-7137-7281

⨯
Stephanie Loomis,

Affiliation Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA, United States of America
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Constance Turman,

Affiliations Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
⨯
Hongyan Huang,

Affiliations Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
⨯
Jinyan Huang,

Affiliations Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
⨯
Hugues Aschard,

Affiliations Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
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Andrew T. Chan,

Affiliation Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, United States of America
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Hyon Choi,

Affiliation Section of Rheumatology and Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, United States of America
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Marilyn Cornelis,

Affiliation Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America
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Gary Curhan,

Affiliations Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America, Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America
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Immaculata De Vivo,

Affiliations Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America
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A. Heather Eliassen,

Affiliations Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America
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Charles Fuchs,

Affiliations Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America, Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, United States of America
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Michael Gaziano,

Affiliation Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America
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Susan E. Hankinson,

Affiliations Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America, Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA, United States of America
⨯
Frank Hu,

Affiliations Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
⨯
Majken Jensen,

Affiliations Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America, Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
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Jae H. Kang,

Affiliation Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America
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Christopher Kabrhel,

Affiliations Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America, Department of Emergency Medicine, Center for Vascular Emergencies, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America
⨯
Liming Liang,

Affiliations Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
⨯
Louis R. Pasquale,

Affiliations Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America
⨯
Eric Rimm,

Affiliations Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America, Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
⨯
Meir J. Stampfer,

Affiliations Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America, Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
⨯
Rulla M. Tamimi,

Affiliations Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America
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Shelley S. Tworoger,

Affiliations Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America
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Janey L. Wiggs,

Affiliation Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA, United States of America
⨯
David J. Hunter,

Affiliations Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America, Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
⨯
[ ... ],
Peter Kraft

Affiliations Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America, Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America
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A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts

Sara Lindström,
Stephanie Loomis,
Constance Turman,
Hongyan Huang,
Jinyan Huang,
Hugues Aschard,
Andrew T. Chan,
Hyon Choi,
Marilyn Cornelis,
Gary Curhan

Published: March 16, 2017
https://doi.org/10.1371/journal.pone.0173997
See the preprint

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