Pyrrolidine dithiocarbamate administered during ex-vivo lung perfusion promotes rehabilitation of injured donor rat lungs obtained after prolonged warm ischemia

Cyril Francioli; Xingyu Wang; Roumen Parapanov; Etienne Abdelnour; Jérôme Lugrin; Fabrizio Gronchi; Jean Perentes; Philippe Eckert; Hans-Beat Ris; Lise Piquilloud; Thorsten Krueger; Lucas Liaudet

doi:10.1371/journal.pone.0173916

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Peer-reviewed

Research Article

Pyrrolidine dithiocarbamate administered during ex-vivo lung perfusion promotes rehabilitation of injured donor rat lungs obtained after prolonged warm ischemia

Cyril Francioli,

Affiliation Service of Thoracic Surgery, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Xingyu Wang,

Affiliation Service of Thoracic Surgery, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Roumen Parapanov,

Affiliations Service of Thoracic Surgery, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland, Service of Adult Intensive Care Medicine, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Etienne Abdelnour,

Affiliation Service of Thoracic Surgery, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Jérôme Lugrin,

Affiliation Service of Adult Intensive Care Medicine, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Fabrizio Gronchi,

Affiliation Service of Anesthesiology, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Jean Perentes,

Affiliation Service of Thoracic Surgery, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Philippe Eckert,

Affiliation Service of Adult Intensive Care Medicine, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Hans-Beat Ris,

Affiliation Service of Thoracic Surgery, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Lise Piquilloud,

Affiliation Service of Adult Intensive Care Medicine, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Thorsten Krueger ,

Contributed equally to this work with: Thorsten Krueger, Lucas Liaudet

Affiliation Service of Thoracic Surgery, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland
⨯
Lucas Liaudet

Contributed equally to this work with: Thorsten Krueger, Lucas Liaudet

* E-mail: lucas.liaudet@chuv.ch

Affiliation Service of Adult Intensive Care Medicine, University Hospital Medical Center and Faculty of Biology and Medicine, Lausanne, Switzerland

http://orcid.org/0000-0003-2670-4930

⨯

Pyrrolidine dithiocarbamate administered during ex-vivo lung perfusion promotes rehabilitation of injured donor rat lungs obtained after prolonged warm ischemia

Cyril Francioli,
Xingyu Wang,
Roumen Parapanov,
Etienne Abdelnour,
Jérôme Lugrin,
Fabrizio Gronchi,
Jean Perentes,
Philippe Eckert,
Hans-Beat Ris,
Lise Piquilloud

Published: March 21, 2017
https://doi.org/10.1371/journal.pone.0173916

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Lung transplantation
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Edema
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Reperfusion injury
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