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Open Access
Peer-reviewed
Research Article
Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers
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Fanny Chereau,
Affiliation Université Paris-Saclay, and Université Paris-Sud and Université de Versailles Saint-Quentin-en-Yvelines, and CESP, INSERM U1018, Kremlin-Bicêtre, France
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Yoann Madec,
Affiliation Emerging Diseases Epidemiology Unit, Institut Pasteur, Paris, France
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Caroline Sabin,
Affiliation Research Department of Infection and Population Health, UCL, Royal Free Campus, Rowland Hill Street, London, United Kingdom
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Niels Obel,
Affiliation Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
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Ezequiel Ruiz-Mateos,
Affiliation Laboratory of Immunovirology, Clinic Unit of Infectious Diseases, Microbiology and Preventive Medecine, Institute of Biomedecine of Seville, IBiS, Virgen del Rocío University Hospital/CSIC/University of Seville, Seville, Spain
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Georgios Chrysos,
Affiliation Department of Medicine, Infectious Disease Unit, Tzaneio General Hospital of Piraeus, Piraeus, Greece
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Sarah Fidler,
Affiliation Imperial College, London, United Kingdom
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Clara Lehmann,
Affiliation Department of Internal Medicine I, University of Cologne and German Center for Infection Research (DZIF), partner site Bonn-Cologne, Cologne, Germany
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Robert Zangerle,
Affiliation Department of Dermatology and Venereology, Medical University Innsbruck, Innsbruck, Austria
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Linda Wittkop,
Affiliation University Bordeaux, ISPED, INSERM U1219-Bordeaux Population Health, INSERM, ISPED, Centre INSERM U1219-Bordeaux Population Health, CHU de Bordeaux, Pole de santé publique, Service d’information médicale, Bordeaux, France
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Peter Reiss,
Affiliation Stichting HIV Monitoring, Amsterdam, the Netherlands, and Department of Global Health, Academic Medical Center, Amsterdam, the Netherlands
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Osamah Hamouda,
Affiliation Robert Koch Institute, Department for Infectious Disease Epidemiology, Berlin, Germany
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Vicente Estrada Perez,
Affiliation Hospital Clinico San Carlos, IdISSC/Universidad Complutense, Madrid, Spain
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Manuel Leal,
Affiliation Laboratory of Immunovirology, Clinic Unit of Infectious Diseases, Microbiology and Preventive Medecine, Institute of Biomedecine of Seville, IBiS, Virgen del Rocío University Hospital/CSIC/University of Seville, Seville, Spain
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Amanda Mocroft,
Affiliation Research Department of Infection and Population Health, UCL, Royal Free Campus, Rowland Hill Street, London, United Kingdom
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Patricia Garcia De Olalla,
Affiliation Epidemiology Service, Public Health Agency of Barcelona, Barcelona and CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain
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Adriana Ammassari,
Affiliation Istituto Nazionale Malattie Infettive L. Spallanzani, IRCCS, Roma, Italy
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Antonella D’Arminio Monforte,
Affiliation Infectious Diseases Unit, Department of Health Sciences, ASST Santi Paolo e Carlo, University Hospital, Milan, Italy
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Cristina Mussini,
Affiliation Clinic of Infectious diseases, University of Modena and Reggio Emilia, Modena, Italy
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Ferran Segura,
Affiliation Infectious Diseases Service, Parc Taulí Hospital Universitario and Universidad Autónoma de Barcelona, Barcelona, Spain
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Antonella Castagna,
Affiliation San Raffaele Vita Salute University, Milano, Italy
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Matthias Cavassini,
Affiliation Infectious Diseases Service, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland
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Sophie Grabar,
Affiliation INSERM, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and UPMC Université Paris 06, and Université Paris Descartes, Hôpital Cochin Hôtel-Dieu Paris, Paris, France
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Philippe Morlat,
Affiliation Service de médecine interne et maladies infectieuses, CHU de Bordeaux, Université de Bordeaux, Inserm U1219, Bordeaux, France
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Stéphane De Wit,
Affiliation Department of Infectious Diseases, St Pierre University Hospital, Université Libre de Bruxelles, Brussels, Belgium
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Olivier Lambotte,
Affiliation Université Paris Sud, UMR 1184, Le Kremlin-Bicêtre, and CEA, DSV/iMETI, IDMIT, Fontenay-aux-Roses, and INSERM, U1184, Immunology of Viral Infections and Autoimmune Diseases, Le Kremlin-Bicêtre, France and Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service de Médecine Interne et Immunologie clinique, Le Kremlin-Bicêtre, France
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Laurence Meyer ,
* E-mail: laurence.meyer@inserm.fr
Affiliation Université Paris-Saclay, and Université Paris-Sud and Université de Versailles Saint-Quentin-en-Yvelines, and CESP, INSERM U1018, Kremlin-Bicêtre, France
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The HIV Controllers Project Working Group for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCOORD
¶Membership of The HIV Controllers Project Working Group for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCOORD can be found within the Acknowledgments section.
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Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers
- Fanny Chereau,
- Yoann Madec,
- Caroline Sabin,
- Niels Obel,
- Ezequiel Ruiz-Mateos,
- Georgios Chrysos,
- Sarah Fidler,
- Clara Lehmann,
- Robert Zangerle,
- Linda Wittkop
- Published: April 5, 2017
- https://doi.org/10.1371/journal.pone.0173893