Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients

Open Access

Peer-reviewed

Research Article

Lai Fun Thean,

Affiliation Department of Colorectal Surgery, Singapore General Hospital, Singapore
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Yu Hui Wong,

Affiliation Department of Colorectal Surgery, Singapore General Hospital, Singapore
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Michelle Lo,

Affiliation Department of Colorectal Surgery, Singapore General Hospital, Singapore
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Carol Loi,

Affiliation Department of Colorectal Surgery, Singapore General Hospital, Singapore
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Min Hoe Chew,

Affiliation Department of Colorectal Surgery, Singapore General Hospital, Singapore
⨯
Choong Leong Tang,

Affiliation Department of Colorectal Surgery, Singapore General Hospital, Singapore
⨯
Peh Yean Cheah

* E-mail: cheah.peh.yean@sgh.com.sg

Affiliations Department of Colorectal Surgery, Singapore General Hospital, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Duke-NUS Medical School, National University of Singapore, Singapore
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Antigen-presenting cells
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Colorectal cancer
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Tumor suppressor genes
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Chromosomal deletions
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Long non-coding RNA
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Polymerase chain reaction
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Deletion mutation
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Genomics
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