Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies

Aizati N. A. Daud; Jorieke E. H. Bergman; Monika P. Oktora; Wilhelmina S. Kerstjens-Frederikse; Henk Groen; Jens H. Bos; Eelko Hak; Bob Wilffert

doi:10.1371/journal.pone.0173530

Loading metrics

Open Access

Peer-reviewed

Research Article

Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies

Aizati N. A. Daud ,

* E-mail: aizati.daud@gmail.com

Affiliations University of Groningen, Groningen Research Institute of Pharmacy, PharmacoTherapy, -Epidemiology & -Economics, Groningen, the Netherlands, Universiti Sains Malaysia, School of Pharmaceutical Sciences, Discipline of Clinical Pharmacy, Penang, Malaysia

http://orcid.org/0000-0003-4336-9468

⨯
Jorieke E. H. Bergman,

Affiliation University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
⨯
Monika P. Oktora,

Affiliation University of Groningen, Groningen Research Institute of Pharmacy, PharmacoTherapy, -Epidemiology & -Economics, Groningen, the Netherlands
⨯
Wilhelmina S. Kerstjens-Frederikse,

Affiliation University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
⨯
Henk Groen,

Affiliation University of Groningen, University Medical Centre Groningen, Department of Epidemiology, Groningen, the Netherlands
⨯
Jens H. Bos,

Affiliation University of Groningen, Groningen Research Institute of Pharmacy, PharmacoTherapy, -Epidemiology & -Economics, Groningen, the Netherlands
⨯
Eelko Hak,

Affiliation University of Groningen, Groningen Research Institute of Pharmacy, PharmacoTherapy, -Epidemiology & -Economics, Groningen, the Netherlands
⨯
Bob Wilffert

Affiliations University of Groningen, Groningen Research Institute of Pharmacy, PharmacoTherapy, -Epidemiology & -Economics, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
⨯

Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies

Aizati N. A. Daud,
Jorieke E. H. Bergman,
Monika P. Oktora,
Wilhelmina S. Kerstjens-Frederikse,
Henk Groen,
Jens H. Bos,
Eelko Hak,
Bob Wilffert

Published: March 13, 2017
https://doi.org/10.1371/journal.pone.0173530

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Pregnancy
Is the Subject Area "Pregnancy" applicable to this article?

Thanks for your feedback.
Drug interactions
Is the Subject Area "Drug interactions" applicable to this article?

Thanks for your feedback.
Congenital anomalies
Is the Subject Area "Congenital anomalies" applicable to this article?

Thanks for your feedback.
Placenta
Is the Subject Area "Placenta" applicable to this article?

Thanks for your feedback.
Cancer risk factors
Is the Subject Area "Cancer risk factors" applicable to this article?

Thanks for your feedback.
Anions
Is the Subject Area "Anions" applicable to this article?

Thanks for your feedback.
Protein expression
Is the Subject Area "Protein expression" applicable to this article?

Thanks for your feedback.
Netherlands
Is the Subject Area "Netherlands" applicable to this article?

Thanks for your feedback.