Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain

• Kevin D. Broad ,

  Contributed equally to this work with: Kevin D. Broad, Go Kawano

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Go Kawano ,

  Contributed equally to this work with: Kevin D. Broad, Go Kawano

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Igor Fierens,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Eridan Rocha-Ferreira,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Mariya Hristova,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Mojgan Ezzati,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Jamshid Rostami,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Daniel Alonso-Alconada,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Badr Chaban,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Jane Hassell,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Bobbi Fleiss,

  Affiliations Centre for the Developing Brain, Kings College, St Thomas Campus, London, United Kingdom, Inserm, U1141, Paris, France, University Paris Diderot, Sorbonne Paris Cite, UMRS 1141, Paris, France

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• Pierre Gressens,

  Affiliations Centre for the Developing Brain, Kings College, St Thomas Campus, London, United Kingdom, Inserm, U1141, Paris, France, University Paris Diderot, Sorbonne Paris Cite, UMRS 1141, Paris, France

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• Robert D. Sanders,

  Affiliation Department of Anesthesiology, University of Wisconsin, Madison, Wisconsin, United States of America

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• Nicola J. Robertson

  * E-mail: n.robertson@ucl.ac.uk

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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