Melanoma cells undergo aggressive coalescence in a 3D Matrigel model that is repressed by anti-CD44

Deborah Wessels; Daniel F. Lusche; Edward Voss; Spencer Kuhl; Emma C. Buchele; Michael R. Klemme; Kanoe B. Russell; Joseph Ambrose; Benjamin A. Soll; Aaron Bossler; Mohammed Milhem; Charles Goldman; David R. Soll

doi:10.1371/journal.pone.0173400

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Open Access

Peer-reviewed

Research Article

Melanoma cells undergo aggressive coalescence in a 3D Matrigel model that is repressed by anti-CD44

Deborah Wessels ,

Contributed equally to this work with: Deborah Wessels, Daniel F. Lusche

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America
⨯
Daniel F. Lusche ,

Contributed equally to this work with: Deborah Wessels, Daniel F. Lusche

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America
⨯
Edward Voss,

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America
⨯
Spencer Kuhl,

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America
⨯
Emma C. Buchele,

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America
⨯
Michael R. Klemme,

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America
⨯
Kanoe B. Russell,

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America
⨯
Joseph Ambrose,

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America
⨯
Benjamin A. Soll,

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America
⨯
Aaron Bossler,

Affiliation Department of Molecular Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA United States of America
⨯
Mohammed Milhem,

Affiliation Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA United States of America
⨯
Charles Goldman,

Affiliation Mercy Hospital System of Des Moines, Des Moines, IA United States of America
⨯
David R. Soll

* E-mail: david-soll@uiowa.edu

Affiliation Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, IA United States of America

http://orcid.org/0000-0002-5059-0315

⨯

Melanoma cells undergo aggressive coalescence in a 3D Matrigel model that is repressed by anti-CD44

Deborah Wessels,
Daniel F. Lusche,
Edward Voss,
Spencer Kuhl,
Emma C. Buchele,
Michael R. Klemme,
Kanoe B. Russell,
Joseph Ambrose,
Benjamin A. Soll,
Aaron Bossler

Published: March 6, 2017
https://doi.org/10.1371/journal.pone.0173400

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