Formulation and PEGylation optimization of the therapeutic PEGylated phenylalanine ammonia lyase for the treatment of phenylketonuria

• Sean M. Bell ,

  * E-mail: sbell@bmrn.com

  Affiliation BioMarin Pharmaceutical, Novato, California, United States of America

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• Dan J. Wendt,

  Affiliation BioMarin Pharmaceutical, Novato, California, United States of America

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• Yanhong Zhang,

  Affiliation BioMarin Pharmaceutical, Novato, California, United States of America

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• Timothy W. Taylor †,

  † Deceased.

  Affiliation BioMarin Pharmaceutical, Novato, California, United States of America

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• Shinong Long,

  Affiliation BioMarin Pharmaceutical, Novato, California, United States of America

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• Laurie Tsuruda,

  Affiliation BioMarin Pharmaceutical, Novato, California, United States of America

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• Bin Zhao,

  Current address: BioZ Consulting, San Ramon, California, United States of America

  Affiliation BioMarin Pharmaceutical, Novato, California, United States of America

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• Phillip Laipis,

  Affiliation Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, United States of America

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• Paul A. Fitzpatrick

  Affiliation BioMarin Pharmaceutical, Novato, California, United States of America

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