Activation of G protein-coupled estrogen receptor 1 induces coronary artery relaxation via Epac/Rap1-mediated inhibition of RhoA/Rho kinase pathway in parallel with PKA

• Xuan Yu,

  Affiliation Department of Physiology and Pharmacology, Texas A&M University, College Station, TX, United States of America

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• Qiao Zhang,

  Affiliations Department of Physiology and Pharmacology, Texas A&M University, College Station, TX, United States of America, Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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• Yan Zhao,

  Affiliations Department of Physiology and Pharmacology, Texas A&M University, College Station, TX, United States of America, Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China

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• Benjamin J. Schwarz,

  Affiliation Department of Physiology and Pharmacology, Texas A&M University, College Station, TX, United States of America

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• John N. Stallone,

  Affiliations Department of Physiology and Pharmacology, Texas A&M University, College Station, TX, United States of America, Women's Health Division, Michael E. DeBakey Institute, Texas A&M University, College Station, TX, United States of America

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• Cristine L. Heaps,

  Affiliation Department of Physiology and Pharmacology, Texas A&M University, College Station, TX, United States of America

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• Guichun Han

  * E-mail: ghan@cvm.tamu.edu

  Affiliations Department of Physiology and Pharmacology, Texas A&M University, College Station, TX, United States of America, Women's Health Division, Michael E. DeBakey Institute, Texas A&M University, College Station, TX, United States of America

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