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Open Access
Peer-reviewed
Research Article
Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function
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Noora Ottman,
Affiliations Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands, Department of Biosciences, University of Helsinki, Helsinki, Finland, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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Justus Reunanen,
Affiliation Cancer and Translational Medicine Research Unit, Biocenter Oulu and Faculty of Medicine, University of Oulu, Oulu, Finland
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Marjolein Meijerink,
Affiliations Host-Microbe Interactomics, Animal Sciences, Wageningen University, Wageningen, The Netherlands, Department Risk Analysis for Products in Development, TNO, Zeist, the Netherlands
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Taija E. Pietilä,
Affiliation Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
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Veera Kainulainen,
Affiliation Pharmacology, Faculty of Medicine, University of Helsinki, Helsinki, Finland
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Judith Klievink,
Affiliations Department of Bacteriology and Immunology, and Research Programs Unit, Immunobiology, University of Helsinki, Helsinki, Finland, Hematology Research Unit Helsinki, University of Helsinki and Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
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Laura Huuskonen,
Affiliation Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
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Steven Aalvink,
Affiliation Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands
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Mikael Skurnik,
Affiliations Department of Bacteriology and Immunology, and Research Programs Unit, Immunobiology, University of Helsinki, Helsinki, Finland, Helsinki University Central Hospital Laboratory Diagnostics, Helsinki, Finland
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Sjef Boeren,
Affiliation Laboratory of Biochemistry, Wageningen University, Wageningen, The Netherlands
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Reetta Satokari,
Affiliation Department of Bacteriology and Immunology, and Research Programs Unit, Immunobiology, University of Helsinki, Helsinki, Finland
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Annick Mercenier,
Affiliation Host-Microbe Interactomics, Animal Sciences, Wageningen University, Wageningen, The Netherlands
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Airi Palva,
Affiliation Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
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Hauke Smidt,
Affiliation Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands
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Willem M. de Vos,
Affiliations Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands, Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland, Department of Bacteriology and Immunology, and Research Programs Unit, Immunobiology, University of Helsinki, Helsinki, Finland
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Clara Belzer
* E-mail: clara.belzer@wur.nl
Affiliation Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands
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Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function
- Noora Ottman,
- Justus Reunanen,
- Marjolein Meijerink,
- Taija E. Pietilä,
- Veera Kainulainen,
- Judith Klievink,
- Laura Huuskonen,
- Steven Aalvink,
- Mikael Skurnik,
- Sjef Boeren
- Published: March 1, 2017
- https://doi.org/10.1371/journal.pone.0173004