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Open Access
Peer-reviewed
Research Article
Critical role of intestinal interleukin-4 modulating regulatory T cells for desensitization, tolerance, and inflammation of food allergy
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Haruyo Nakajima-Adachi ,
Contributed equally to this work with: Haruyo Nakajima-Adachi, Kyoko Shibahara
* E-mail: aryu@mail.ecc.u-tokyo.ac.jp
Affiliations Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan, Department of Microbiology and Immunology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
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Kyoko Shibahara ,
Contributed equally to this work with: Haruyo Nakajima-Adachi, Kyoko Shibahara
Affiliations Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan, Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
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Yoko Fujimura,
Affiliation Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
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Jun Takeyama,
Affiliations Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan, Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
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Erika Hiraide,
Affiliations Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan, Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
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Akira Kikuchi,
Affiliation Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
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Hitoshi Murakami,
Affiliations Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan, Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan, Department of Food Bioscience and Biotechnology, Nihon University, Kanagawa, Japan
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Akira Hosono,
Affiliation Department of Food Bioscience and Biotechnology, Nihon University, Kanagawa, Japan
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Tomonori Nochi,
Affiliation Department of Microbiology and Immunology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
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Yoshio Wakatsuki,
Affiliation Department of Clinical Bio-regulatory Science, Kyoto University Graduate School of Medicine, Kyoto, Japan
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Naoki Shimojo,
Affiliation The Department of Pediatrics, Chiba University, Chiba, Japan
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Shuichi Kaminogawa,
Affiliation Department of Food Bioscience and Biotechnology, Nihon University, Kanagawa, Japan
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Ryuichiro Sato,
Affiliation Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
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Hiroshi Kiyono,
Affiliations Department of Microbiology and Immunology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, Tokyo, Japan, International Research and Development Center for Mucosal Vaccines, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, Department of Medical Genome Science, Graduate School of Frontier Science, The University of Tokyo, Tokyo, Japan, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
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Satoshi Hachimura
Affiliations Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan, Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
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Critical role of intestinal interleukin-4 modulating regulatory T cells for desensitization, tolerance, and inflammation of food allergy
- Haruyo Nakajima-Adachi,
- Kyoko Shibahara,
- Yoko Fujimura,
- Jun Takeyama,
- Erika Hiraide,
- Akira Kikuchi,
- Hitoshi Murakami,
- Akira Hosono,
- Tomonori Nochi,
- Yoshio Wakatsuki
- Published: February 24, 2017
- https://doi.org/10.1371/journal.pone.0172795