Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients

Crismita Dmello; Sharada Sawant; Hunain Alam; Prakash Gangadaran; Saie Mogre; Richa Tiwari; Zinia D’Souza; Manish Narkar; Rahul Thorat; Komal Patil; Devendra Chaukar; Shubhada Kane; Milind Vaidya

doi:10.1371/journal.pone.0172559

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Open Access

Peer-reviewed

Research Article

Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients

Crismita Dmello,

Affiliations Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India, Homi Bhabha National Institute, Training school complex, Anushakti Nagar, Mumbai, India
⨯
Sharada Sawant,

Affiliations Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India, Homi Bhabha National Institute, Training school complex, Anushakti Nagar, Mumbai, India
⨯
Hunain Alam,

Current address: Department of Molecular and Cellular Oncology, MD Anderson Cancer Centre, University of Texas, Houston, Texas, United States of America

Affiliation Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India
⨯
Prakash Gangadaran,

Current address: Department of Nuclear Medicine, Kyunpook National University school of Medicine, N101, Dongin-Dong, Jung-Gu, Daegu, Republic of Korea

Affiliation Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India
⨯
Saie Mogre,

Affiliation Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India
⨯
Richa Tiwari,

Affiliations Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India, Homi Bhabha National Institute, Training school complex, Anushakti Nagar, Mumbai, India
⨯
Zinia D’Souza,

Affiliation Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India
⨯
Manish Narkar,

Affiliation Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India
⨯
Rahul Thorat,

Affiliation Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India
⨯
Komal Patil,

Affiliation Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India
⨯
Devendra Chaukar,

Affiliations Homi Bhabha National Institute, Training school complex, Anushakti Nagar, Mumbai, India, Surgical Oncology, Head and Neck Unit, Tata Memorial Hospital (TMH), Parel, Mumbai, India
⨯
Shubhada Kane,

Affiliations Homi Bhabha National Institute, Training school complex, Anushakti Nagar, Mumbai, India, Department of Pathology, Tata Memorial Hospital (TMH), Parel, Mumbai, India
⨯
Milind Vaidya

* E-mail: mvaidya@actrec.gov.in

Affiliations Cancer Research Institute (CRI), Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, India, Homi Bhabha National Institute, Training school complex, Anushakti Nagar, Mumbai, India
⨯

Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients

Crismita Dmello,
Sharada Sawant,
Hunain Alam,
Prakash Gangadaran,
Saie Mogre,
Richa Tiwari,
Zinia D’Souza,
Manish Narkar,
Rahul Thorat,
Komal Patil

Published: February 22, 2017
https://doi.org/10.1371/journal.pone.0172559

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