Safety evaluation of a vaccine: Effect in maternal reproductive outcome and fetal anomaly frequency in rats using a leishmanial vaccine as a model

• Rafaianne Q. Moraes-Souza ,

  Contributed equally to this work with: Rafaianne Q. Moraes-Souza, Ana Paula Reinaque

  Affiliation Laboratory of System Physiology and Reproductive Toxicology, Institute of Biological and Health Sciences, Federal University of Mato Grosso (UFMT) - Barra do Garças, Mato Grosso State, Brazil

  ⨯
• Ana Paula Reinaque ,

  Contributed equally to this work with: Rafaianne Q. Moraes-Souza, Ana Paula Reinaque

  Affiliation Laboratory of Immunology and Genomics of Parasites, Department of Parasitology, Biological Sciences Institute, Federal University of Minas Gerais (UFMG) Belo Horizonte, Minas Gerais State, Brazil

  ⨯
• Thaigra S. Soares,

  Affiliation Laboratory of System Physiology and Reproductive Toxicology, Institute of Biological and Health Sciences, Federal University of Mato Grosso (UFMT) - Barra do Garças, Mato Grosso State, Brazil

  ⨯
• Ana Luiza T. Silva,

  Affiliation Laboratory of Immunology and Genomics of Parasites, Department of Parasitology, Biological Sciences Institute, Federal University of Minas Gerais (UFMG) Belo Horizonte, Minas Gerais State, Brazil

  ⨯
• Rodolfo C. Giunchetti,

  Affiliation Laboratory of Cell-Cell Interactions, Morphology Department, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

  ⨯
• Maria A. S. Takano,

  Affiliation Division of Technological Development and Production (DDTP), Butantan Institute, São Paulo, Brazil

  ⨯
• Milena A. Akamatsu,

  Affiliation Division of Technological Development and Production (DDTP), Butantan Institute, São Paulo, Brazil

  ⨯
• Flávia S. Kubrusly,

  Affiliation Division of Technological Development and Production (DDTP), Butantan Institute, São Paulo, Brazil

  ⨯
• Fernanda Lúcio-Macarini,

  Affiliation Division of Technological Development and Production (DDTP), Butantan Institute, São Paulo, Brazil

  ⨯
• Isaias Raw,

  Affiliation Division of Technological Development and Production (DDTP), Butantan Institute, São Paulo, Brazil

  ⨯
• Dmitri Iourtov,

  Affiliation Division of Technological Development and Production (DDTP), Butantan Institute, São Paulo, Brazil

  ⨯
• Paulo Lee Ho,

  Affiliation Division of Technological Development and Production (DDTP), Butantan Institute, São Paulo, Brazil

  ⨯
• Lilian L. Bueno,

  Affiliation Laboratory of Immunology and Genomics of Parasites, Department of Parasitology, Biological Sciences Institute, Federal University of Minas Gerais (UFMG) Belo Horizonte, Minas Gerais State, Brazil

  ⨯
• Ricardo T. Fujiwara,

  Affiliation Laboratory of Immunology and Genomics of Parasites, Department of Parasitology, Biological Sciences Institute, Federal University of Minas Gerais (UFMG) Belo Horizonte, Minas Gerais State, Brazil

  ⨯
• Gustavo T. Volpato

  * E-mail: gtvolpato@yahoo.com

  Affiliation Laboratory of System Physiology and Reproductive Toxicology, Institute of Biological and Health Sciences, Federal University of Mato Grosso (UFMT) - Barra do Garças, Mato Grosso State, Brazil

  ⨯