Ultra-deep sequencing reveals high prevalence and broad structural diversity of hepatitis B surface antigen mutations in a global population

• Mikael Gencay,

  Affiliation Roche Diagnostics International Ltd, Rotkreuz, Switzerland

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• Kirsten Hübner,

  Affiliation Bioscientia Institute for Medical Diagnostics, Ingelheim, Germany

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• Peter Gohl,

  Affiliation Bioscientia Institute for Medical Diagnostics, Ingelheim, Germany

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• Anja Seffner,

  Affiliation Department of Molecular Genetics and Microbiology, MVZ Labor Dr. Limbach & Kollegen GbR, Heidelberg, Germany

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• Michael Weizenegger,

  Affiliation Department of Molecular Genetics and Microbiology, MVZ Labor Dr. Limbach & Kollegen GbR, Heidelberg, Germany

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• Dionysios Neofytos,

  Affiliation Roche Diagnostics International Ltd, Rotkreuz, Switzerland

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• Richard Batrla,

  Affiliation Roche Diagnostics International Ltd, Rotkreuz, Switzerland

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• Andreas Woeste,

  Affiliation Roche Diagnostics GmbH, Penzberg, Germany

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• Hyon-suk Kim,

  Affiliation Department of Laboratory Medicine, Yonsei University College of Medicine, Severance Hospital, Seoul, South Korea

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• Gaston Westergaard,

  Affiliation Roche Diagnostics International Ltd, Rotkreuz, Switzerland

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• Christine Reinsch,

  Affiliation Roche Diagnostics GmbH, Mannheim, Germany

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• Eva Brill,

  Affiliation Bioscientia Institute for Medical Diagnostics, Ingelheim, Germany

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• Pham Thi Thu Thuy,

  Affiliation Hepatology Department, Medic Medical Center, Ho Chi Minh City, Vietnam

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• Bui Huu Hoang,

  Affiliation Gastroenterology Department, Ho Chi Minh City University Medical Center, Ho Chi Minh City, Vietnam

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• Mark Sonderup,

  Affiliation Division of Hepatology and Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa

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• C. Wendy Spearman,

  Affiliation Division of Hepatology and Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa

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• Stephan Pabinger,

  Affiliation AIT Austrian Institute of Technology, Health and Environment Department, Molecular Diagnostics, Vienna, Austria

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• Jérémie Gautier,

  Affiliation Cerba Spécimen Services, Saint-Ouen l'Aumône, France

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• Giuseppina Brancaccio,

  Affiliation Infectious Diseases and Viral Hepatitis Unit, Second University of Naples, Naples, Italy

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• Massimo Fasano,

  Affiliation Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy

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• Teresa Santantonio,

  Affiliation Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy

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• Giovanni B. Gaeta,

  Affiliation Infectious Diseases and Viral Hepatitis Unit, Second University of Naples, Naples, Italy

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• Markus Nauck ,

  * E-mail: wolfgang.kaminski@bioscientia.de (WEK); markus.nauck@bioscientia.de (MN)

  Affiliation Bioscientia Institute for Medical Diagnostics, Ingelheim, Germany

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•  [ ... ],
• Wolfgang E. Kaminski

  * E-mail: wolfgang.kaminski@bioscientia.de (WEK); markus.nauck@bioscientia.de (MN)

  Affiliation Bioscientia Institute for Medical Diagnostics, Ingelheim, Germany

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