Prospects and limitations of improving skeletal growth in a mouse model of spondyloepiphyseal dysplasia caused by R992C (p.R1192C) substitution in collagen II

Open Access

Peer-reviewed

Research Article

Machiko Arita ,

Contributed equally to this work with: Machiko Arita, Jolanta Fertala

Affiliation Department of Orthopaedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Jolanta Fertala ,

Contributed equally to this work with: Machiko Arita, Jolanta Fertala

Affiliation Department of Orthopaedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Cheryl Hou,

Affiliation Department of Orthopaedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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James Kostas,

Affiliation Department of Orthopaedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Andrzej Steplewski,

Affiliation Department of Orthopaedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Andrzej Fertala

* E-mail: andrzej.fertala@jefferson.edu

Affiliation Department of Orthopaedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Collagens
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Growth plate
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Chondrocytes
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Mouse models
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Extracellular matrix
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Dysplasia
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Cartilage
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Skull
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