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Open Access

Peer-reviewed

Research Article

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer

Nivedita Arora,

Affiliation Div. of Basic and Translational Research Dept. of Surgery University of Minnesota, Minneapolis MN, United States of America
⨯
Osama Alsaied,

Affiliation Div. of Basic and Translational Research Dept. of Surgery University of Minnesota, Minneapolis MN, United States of America
⨯
Patricia Dauer,

Affiliations Div. of Basic and Translational Research Dept. of Surgery University of Minnesota, Minneapolis MN, United States of America, Div. of Surgical Oncology Dept. of Surgery University of Miami, Miami, FL, United States of America
⨯
Kaustav Majumder,

Affiliation Div. of Basic and Translational Research Dept. of Surgery University of Minnesota, Minneapolis MN, United States of America
⨯
Shrey Modi,

Affiliations Div. of Basic and Translational Research Dept. of Surgery University of Minnesota, Minneapolis MN, United States of America, Div. of Surgical Oncology Dept. of Surgery University of Miami, Miami, FL, United States of America
⨯
Bhuwan Giri,

Affiliations Div. of Basic and Translational Research Dept. of Surgery University of Minnesota, Minneapolis MN, United States of America, Div. of Surgical Oncology Dept. of Surgery University of Miami, Miami, FL, United States of America
⨯
Vikas Dudeja,

Affiliations Div. of Basic and Translational Research Dept. of Surgery University of Minnesota, Minneapolis MN, United States of America, Div. of Surgical Oncology Dept. of Surgery University of Miami, Miami, FL, United States of America
⨯
Sulagna Banerjee,

Affiliations Div. of Basic and Translational Research Dept. of Surgery University of Minnesota, Minneapolis MN, United States of America, Div. of Surgical Oncology Dept. of Surgery University of Miami, Miami, FL, United States of America
⨯
Daniel Von Hoff,

Affiliation TGen/Virginia G. Piper Cancer Ctr, Suite 600, Phoenix, AZ United States of America
⨯
Ashok Saluja

* E-mail: asaluja@miami.edu

Affiliations Div. of Basic and Translational Research Dept. of Surgery University of Minnesota, Minneapolis MN, United States of America, Div. of Surgical Oncology Dept. of Surgery University of Miami, Miami, FL, United States of America
⨯

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer

Nivedita Arora,
Osama Alsaied,
Patricia Dauer,
Kaustav Majumder,
Shrey Modi,
Bhuwan Giri,
Vikas Dudeja,
Sulagna Banerjee,
Daniel Von Hoff,
Ashok Saluja

x

Published: February 13, 2017
https://doi.org/10.1371/journal.pone.0171827

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Cancer treatment
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Apoptosis
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Mouse models
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Adenocarcinoma cells
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