Revertant mosaicism for family mutations is not observed in BRCA1/2 phenocopies

Jacopo Azzollini; Chiara Pesenti; Luca Ferrari; Laura Fontana; Mariarosaria Calvello; Bernard Peissel; Giorgio Portera; Silvia Tabano; Maria Luisa Carcangiu; Paola Riva; Monica Miozzo; Siranoush Manoukian

doi:10.1371/journal.pone.0171663

Loading metrics

Open Access

Peer-reviewed

Research Article

Revertant mosaicism for family mutations is not observed in BRCA1/2 phenocopies

Jacopo Azzollini,

Affiliation Medical Genetics Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯
Chiara Pesenti,

Affiliation Department of Pathophysiology & Transplantation, Università degli Studi di Milano, Division of Pathology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
⨯
Luca Ferrari,

Affiliation Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy
⨯
Laura Fontana,

Affiliation Department of Pathophysiology & Transplantation, Università degli Studi di Milano, Division of Pathology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
⨯
Mariarosaria Calvello,

Affiliation Medical Genetics Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯
Bernard Peissel,

Affiliation Medical Genetics Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯
Giorgio Portera,

Affiliation Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy
⨯
Silvia Tabano,

Affiliation Department of Pathophysiology & Transplantation, Università degli Studi di Milano, Division of Pathology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
⨯
Maria Luisa Carcangiu,

Affiliation Pathology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯
Paola Riva,

Affiliation Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy
⨯
Monica Miozzo ,

* E-mail: monica.miozzo@unimi.it

Affiliation Department of Pathophysiology & Transplantation, Università degli Studi di Milano, Division of Pathology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

http://orcid.org/0000-0002-6523-4575

⨯
Siranoush Manoukian

Affiliation Medical Genetics Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯

Revertant mosaicism for family mutations is not observed in BRCA1/2 phenocopies

Jacopo Azzollini,
Chiara Pesenti,
Luca Ferrari,
Laura Fontana,
Mariarosaria Calvello,
Bernard Peissel,
Giorgio Portera,
Silvia Tabano,
Maria Luisa Carcangiu,
Paola Riva

Published: February 15, 2017
https://doi.org/10.1371/journal.pone.0171663

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Genetic causes of cancer
Is the Subject Area "Genetic causes of cancer" applicable to this article?

Thanks for your feedback.
Mutant genotypes
Is the Subject Area "Mutant genotypes" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Invasive tumors
Is the Subject Area "Invasive tumors" applicable to this article?

Thanks for your feedback.
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
Is the Subject Area "Matrix-assisted laser desorption ionization time-of-flight mass spectrometry" applicable to this article?

Thanks for your feedback.
Cancer risk factors
Is the Subject Area "Cancer risk factors" applicable to this article?

Thanks for your feedback.
Immune receptors
Is the Subject Area "Immune receptors" applicable to this article?

Thanks for your feedback.
Mutation detection
Is the Subject Area "Mutation detection" applicable to this article?

Thanks for your feedback.