The impact of obesity and adiponectin signaling in patients with renal cell carcinoma: A potential mechanism for the “obesity paradox”

Ryuichi Ito; Shintaro Narita; Mingguo Huang; Taketoshi Nara; Kazuyuki Numakura; Koichiro Takayama; Hiroshi Tsuruta; Atsushi Maeno; Mitsuru Saito; Takamitsu Inoue; Norihiko Tsuchiya; Shigeru Satoh; Tomonori Habuchi

doi:10.1371/journal.pone.0171615

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Open Access

Peer-reviewed

Research Article

The impact of obesity and adiponectin signaling in patients with renal cell carcinoma: A potential mechanism for the “obesity paradox”

Ryuichi Ito,

Affiliation Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Shintaro Narita ,

* E-mail: nari6202@gipc.akita-u.ac.jp

Affiliations Department of Urology, Akita University Graduate School of Medicine, Akita, Japan, AMED-CREST, Japan Agency for Medical Research and Development
⨯
Mingguo Huang,

Affiliations Department of Urology, Akita University Graduate School of Medicine, Akita, Japan, AMED-CREST, Japan Agency for Medical Research and Development
⨯
Taketoshi Nara,

Affiliation Department of Urology, Yamagata University Graduate School of Medicine, Yamagata, Japan
⨯
Kazuyuki Numakura,

Affiliation Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Koichiro Takayama,

Affiliation Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Hiroshi Tsuruta,

Affiliation Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Atsushi Maeno,

Affiliation Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Mitsuru Saito,

Affiliation Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Takamitsu Inoue,

Affiliations Department of Urology, Akita University Graduate School of Medicine, Akita, Japan, AMED-CREST, Japan Agency for Medical Research and Development
⨯
Norihiko Tsuchiya,

Affiliation Department of Urology, Yamagata University Graduate School of Medicine, Yamagata, Japan
⨯
Shigeru Satoh,

Affiliation Center for Kidney Disease and Transplantation, Akita University Hospital, Akita, Japan
⨯
Tomonori Habuchi

Affiliations Department of Urology, Akita University Graduate School of Medicine, Akita, Japan, AMED-CREST, Japan Agency for Medical Research and Development
⨯

The impact of obesity and adiponectin signaling in patients with renal cell carcinoma: A potential mechanism for the “obesity paradox”

Ryuichi Ito,
Shintaro Narita,
Mingguo Huang,
Taketoshi Nara,
Kazuyuki Numakura,
Koichiro Takayama,
Hiroshi Tsuruta,
Atsushi Maeno,
Mitsuru Saito,
Takamitsu Inoue

Published: February 8, 2017
https://doi.org/10.1371/journal.pone.0171615

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Renal cell carcinoma
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