Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease

• Candice Alexandra Grzelak ,

  Contributed equally to this work with: Candice Alexandra Grzelak, Nicholas David Sigglekow

  Affiliation Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia

  http://orcid.org/0000-0001-8645-4297

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• Nicholas David Sigglekow ,

  Contributed equally to this work with: Candice Alexandra Grzelak, Nicholas David Sigglekow

  Affiliation Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia

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• Janina Elke Eleonore Tirnitz-Parker,

  Affiliation School of Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, Bentley, Western Australia, Australia

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• Elizabeth Jane Hamson,

  Affiliation Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia

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• Alessandra Warren,

  Affiliations Ageing and Alzheimers Institute, Centre for Education and Research on Ageing, University of Sydney, Concord Hospital, Sydney, New South Wales, Australia, ANZAC Research Institute, University of Sydney, Concord Hospital, Sydney, New South Wales, Australia

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• Bharvi Maneck,

  Affiliations Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia, A.W. Morrow Gastroenterology and Liver Centre, R.P.A.H., Camperdown, New South Wales, Australia

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• Jinbiao Chen,

  Affiliation Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia

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• Bramilla Patkunanathan,

  Affiliation Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia

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• Jade Boland,

  Affiliation Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia

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• Robert Cheng,

  Affiliation Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia

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• Nicholas Adam Shackel,

  Affiliations Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia, A.W. Morrow Gastroenterology and Liver Centre, R.P.A.H., Camperdown, New South Wales, Australia, Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia

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• Devanshi Seth,

  Affiliation Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia

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• David Geoffrey Bowen,

  Affiliations Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia, A.W. Morrow Gastroenterology and Liver Centre, R.P.A.H., Camperdown, New South Wales, Australia

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• Luciano Gastón Martelotto,

  Affiliation Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• D. Neil Watkins,

  Affiliation The Kinghorn Cancer Centre, Garvan Institute, Darlinghurst, New South Wales, Australia

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•  [ ... ],
• Geoffrey William McCaughan

  * E-mail: g.mccaughan@centenary.org.au

  Affiliations Liver Injury and Cancer, Centenary Institute, Camperdown, New South Wales, Australia, A.W. Morrow Gastroenterology and Liver Centre, R.P.A.H., Camperdown, New South Wales, Australia, Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia

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