TIMP1 and MMP9 are predictors of mortality in septic patients in the emergency department and intensive care unit unlike MMP9/TIMP1 ratio: Multivariate model

Maria Eugenia Niño; Sergio Eduardo Serrano; Daniela Camila Niño; Diana Margarita McCosham; Maria Eugenia Cardenas; Vivian Poleth Villareal; Marcos Lopez; Antonio Pazin-Filho; Fabian Alberto Jaimes; Fernando Cunha; Richard Schulz; Diego Torres-Dueñas

doi:10.1371/journal.pone.0171191

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Peer-reviewed

Research Article

TIMP1 and MMP9 are predictors of mortality in septic patients in the emergency department and intensive care unit unlike MMP9/TIMP1 ratio: Multivariate model

Maria Eugenia Niño ,

Contributed equally to this work with: Maria Eugenia Niño, Sergio Eduardo Serrano, Daniela Camila Niño, Diego Torres-Dueñas

Affiliation Department of Public Health, Medicine Program, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia
⨯
Sergio Eduardo Serrano ,

Contributed equally to this work with: Maria Eugenia Niño, Sergio Eduardo Serrano, Daniela Camila Niño, Diego Torres-Dueñas

Affiliation Department of Public Health, Medicine Program, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia
⨯
Daniela Camila Niño ,

Contributed equally to this work with: Maria Eugenia Niño, Sergio Eduardo Serrano, Daniela Camila Niño, Diego Torres-Dueñas

Affiliation Department of Pharmacology, Medicine Program, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia
⨯
Diana Margarita McCosham,

Affiliation Department of Pharmacology, Medicine Program, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia
⨯
Maria Eugenia Cardenas,

Affiliation Microbiology and Inmunology Department, Medicine Program, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia
⨯
Vivian Poleth Villareal,

Affiliation Department of Pharmacology, Medicine Program, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia
⨯
Marcos Lopez,

Affiliation Biotechnology Department, Enterprise Technology Center, Fundación Cardiovascular de Colombia, Bucaramanga, Santander, Colombia
⨯
Antonio Pazin-Filho,

Affiliation Department of Medical Clinics, Emergency unit, Faculty of Medicine, Universidade de Sao Paulo, Ribeirao preto, Sao Paulo, Brazil
⨯
Fabian Alberto Jaimes,

Affiliation Department of Internal Medicine, School Of Medicine, Universidad de Antioquia, Medellin, Antioquia, Colombia
⨯
Fernando Cunha,

Affiliation Department of Pharmacology, Faculty of Medicine, Universidade de Sao Paulo, Ribeirao preto, Sao Paulo, Brazil
⨯
Richard Schulz,

Affiliation Departments of Pediatrics and Pharmacology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada
⨯
Diego Torres-Dueñas

Contributed equally to this work with: Maria Eugenia Niño, Sergio Eduardo Serrano, Daniela Camila Niño, Diego Torres-Dueñas

* E-mail: dtorres@unab.edu.co

Affiliation Department of Pharmacology, Medicine Program, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia
⨯

TIMP1 and MMP9 are predictors of mortality in septic patients in the emergency department and intensive care unit unlike MMP9/TIMP1 ratio: Multivariate model

Maria Eugenia Niño,
Sergio Eduardo Serrano,
Daniela Camila Niño,
Diana Margarita McCosham,
Maria Eugenia Cardenas,
Vivian Poleth Villareal,
Marcos Lopez,
Antonio Pazin-Filho,
Fabian Alberto Jaimes,
Fernando Cunha

Published: February 13, 2017
https://doi.org/10.1371/journal.pone.0171191

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