Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels

Holly LaDuca; Kelly D. Farwell; Huy Vuong; Hsiao-Mei Lu; Wenbo Mu; Layla Shahmirzadi; Sha Tang; Jefferey Chen; Shruti Bhide; Elizabeth C. Chao

doi:10.1371/journal.pone.0170843

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Open Access

Peer-reviewed

Research Article

Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels

Holly LaDuca ,

* E-mail: hladuca@ambrygen.com (HL); kfarwell@ambrygen.com (KDF)

Affiliation Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United States of America
⨯
Kelly D. Farwell ,

* E-mail: hladuca@ambrygen.com (HL); kfarwell@ambrygen.com (KDF)

Affiliation Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United States of America
⨯
Huy Vuong,

Affiliation Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United States of America
⨯
Hsiao-Mei Lu,

Affiliation Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United States of America
⨯
Wenbo Mu,

Affiliation Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United States of America
⨯
Layla Shahmirzadi,

Affiliation Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United States of America
⨯
Sha Tang,

Affiliation Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United States of America
⨯
Jefferey Chen,

Affiliation Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United States of America
⨯
Shruti Bhide,

Affiliation Department of Clinical Diagnostics, Ambry Genetics, Aliso Viejo, California, United States of America
⨯
Elizabeth C. Chao

Affiliation Department of Pediatrics, Division of Genetics and Genomic Medicine, University of California Irvine, Irvine, California, United States of America
⨯

Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels

Holly LaDuca,
Kelly D. Farwell,
Huy Vuong,
Hsiao-Mei Lu,
Wenbo Mu,
Layla Shahmirzadi,
Sha Tang,
Jefferey Chen,
Shruti Bhide,
Elizabeth C. Chao

Published: February 2, 2017
https://doi.org/10.1371/journal.pone.0170843

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Next-generation sequencing
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Introns
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Nucleotides
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Nucleotide sequencing
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Gene sequencing
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