The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts

Joseph Russo; Jerome E. Lee; Carolina M. López; John Anderson; Thuy-mi P. Nguyen; Adam M. Heck; Jeffrey Wilusz; Carol J. Wilusz

doi:10.1371/journal.pone.0170680

Loading metrics

Open Access

Peer-reviewed

Research Article

The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts

Joseph Russo,

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Jerome E. Lee,

Current Address: ArcherDX, Boulder, Colorado, United States of America

Affiliations Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Carolina M. López,

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
John Anderson,

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Thuy-mi P. Nguyen,

Current Address: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Adam M. Heck,

Affiliations Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Jeffrey Wilusz,

Affiliations Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Carol J. Wilusz

* E-mail: cwilusz@colostate.edu

Affiliations Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America

http://orcid.org/0000-0001-9939-0747

⨯

The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts

Joseph Russo,
Jerome E. Lee,
Carolina M. López,
John Anderson,
Thuy-mi P. Nguyen,
Adam M. Heck,
Jeffrey Wilusz,
Carol J. Wilusz

Published: January 27, 2017
https://doi.org/10.1371/journal.pone.0170680

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Messenger RNA
Is the Subject Area "Messenger RNA" applicable to this article?

Thanks for your feedback.
3' UTR
Is the Subject Area "3' UTR" applicable to this article?

Thanks for your feedback.
Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
Myoblasts
Is the Subject Area "Myoblasts" applicable to this article?

Thanks for your feedback.
RNA-binding proteins
Is the Subject Area "RNA-binding proteins" applicable to this article?

Thanks for your feedback.
Luciferase
Is the Subject Area "Luciferase" applicable to this article?

Thanks for your feedback.
Wound healing
Is the Subject Area "Wound healing" applicable to this article?

Thanks for your feedback.
Cell migration
Is the Subject Area "Cell migration" applicable to this article?

Thanks for your feedback.