Development of a Novel Vaccine Containing Binary Toxin for the Prevention of Clostridium difficile Disease with Enhanced Efficacy against NAP1 Strains

• Susan Secore ,

  * E-mail: susan_secore1@merck.com

  Affiliation Vaccine Basic Research, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

  http://orcid.org/0000-0002-0879-3442

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• Su Wang,

  Current address: Department of Clinical Biodefense, Meso Scale Diagnostics, Gaithersburg, Maryland, United States of America

  Affiliation Vaccine Basic Research, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Julie Doughtry,

  Current address: Translational Research & Development, Bristol-Myers Squibb, Princeton, New Jersey, Princeton, New Jersey, United States of America

  Affiliation Vaccine Basic Research, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Jinfu Xie,

  Affiliation Vaccine Basic Research, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Matt Miezeiewski,

  Current address: Department of Large Molecule Analytical Development, Janssen Research and Development, Malvern, PA, United States of America

  Affiliation Eurofins Laboratories, Lancaster, Pennsylvania, United States of America

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• Richard R. Rustandi,

  Affiliation Vaccine Analytical Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Melanie Horton,

  Affiliation Vaccine Basic Research, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Rachel Xoconostle,

  Current address: Process Development and Analytics, Merck and Company, Incorporated, Durham, North Carolina, United States of America

  Affiliation Vaccine Basic Research, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Bei Wang,

  Affiliation Vaccine Drug Product Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Catherine Lancaster,

  Affiliation Vaccine Analytical Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Adam Kristopeit,

  Affiliation Vaccine Process Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Sheng-Ching Wang,

  Affiliation Vaccine Process Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Sianny Christanti,

  Affiliation Vaccine Process Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Salvatore Vitelli,

  Affiliation Vaccine Analytical Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Marie-Pierre Gentile,

  Current address: Department of Global Biologics Manufacturing Science and Technology, Genentech, San Francisco, California, United States of America

  Affiliation Vaccine Process Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Aaron Goerke,

  Current address: Department of Global Biologics Manufacturing Science and Technology, Genentech, San Francisco, California, United States of America

  Affiliation Vaccine Process Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Julie Skinner,

  Affiliation Vaccine Basic Research, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Erica Strable,

  Affiliation Vaccine Drug Product Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• David S. Thiriot,

  Affiliation Vaccine Drug Product Development, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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• Jean-Luc Bodmer,

  Current address: CMC Analytical Development & QC, Seres Therapeutics, Incorporated, Cambridge, Massachusetts, United States of America

  Affiliation Vaccine Basic Research, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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•  [ ... ],
• Jon H. Heinrichs

  Current address: Global Project Leadership, Sanofi Pasteur, Swiftwater, Pennsylvania, United States of America

  Affiliation Vaccine Basic Research, Merck Research Laboratories, Merck and Company, Incorporated, West Point, Pennsylvania, United States of America

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