Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients

Michael J. Cox; Elena M. Turek; Catherine Hennessy; Ghazala K. Mirza; Phillip L. James; Meg Coleman; Andrew Jones; Robert Wilson; Diana Bilton; William O. C. Cookson; Miriam F. Moffatt; Michael R. Loebinger

doi:10.1371/journal.pone.0170622

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Peer-reviewed

Research Article

Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients

Michael J. Cox,

Affiliation National Heart and Lung Institute, Imperial College London, London, United Kingdom

http://orcid.org/0000-0002-4002-1506

⨯
Elena M. Turek,

Affiliation National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Catherine Hennessy,

Affiliation Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
⨯
Ghazala K. Mirza,

Affiliation National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Phillip L. James,

Affiliations National Heart and Lung Institute, Imperial College London, London, United Kingdom, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
⨯
Meg Coleman,

Affiliation Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
⨯
Andrew Jones,

Affiliation Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
⨯
Robert Wilson,

Affiliation Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
⨯
Diana Bilton,

Affiliations National Heart and Lung Institute, Imperial College London, London, United Kingdom, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
⨯
William O. C. Cookson ,

Contributed equally to this work with: William O. C. Cookson, Miriam F. Moffatt, Michael R. Loebinger

Affiliations National Heart and Lung Institute, Imperial College London, London, United Kingdom, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
⨯
Miriam F. Moffatt ,

Contributed equally to this work with: William O. C. Cookson, Miriam F. Moffatt, Michael R. Loebinger

* E-mail: m.moffatt@imperial.ac.uk (MFM); m.loebinger@imperial.ac.uk (MRL)

Affiliation National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Michael R. Loebinger

Contributed equally to this work with: William O. C. Cookson, Miriam F. Moffatt, Michael R. Loebinger

* E-mail: m.moffatt@imperial.ac.uk (MFM); m.loebinger@imperial.ac.uk (MRL)

Affiliations National Heart and Lung Institute, Imperial College London, London, United Kingdom, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
⨯

Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients

Michael J. Cox,
Elena M. Turek,
Catherine Hennessy,
Ghazala K. Mirza,
Phillip L. James,
Meg Coleman,
Andrew Jones,
Robert Wilson,
Diana Bilton,
William O. C. Cookson

Published: February 7, 2017
https://doi.org/10.1371/journal.pone.0170622

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