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Open Access

Peer-reviewed

Research Article

Knockdown of NIK and IKKβ-Binding Protein (NIBP) Reduces Colorectal Cancer Metastasis through Down-Regulation of the Canonical NF-κΒ Signaling Pathway and Suppression of MAPK Signaling Mediated through ERK and JNK

Mengbin Qin ,

Contributed equally to this work with: Mengbin Qin, Jinxiu Zhang

Affiliation Department of Gastroenterology, The First Affiliated Hospital, Guangxi Medical University, Nanning, China
⨯
Jinxiu Zhang ,

Contributed equally to this work with: Mengbin Qin, Jinxiu Zhang

Affiliation Department of Gastroenterology, The First Affiliated Hospital, Guangxi Medical University, Nanning, China
⨯
Chunyan Xu,

Affiliation Department of Gastroenterology, The First Affiliated Hospital, Guangxi Medical University, Nanning, China
⨯
Peng Peng,

Affiliation Department of Gastroenterology, The First Affiliated Hospital, Guangxi Medical University, Nanning, China
⨯
Lin Tan,

Affiliation Department of Gastroenterology, The First Affiliated Hospital, Guangxi Medical University, Nanning, China
⨯
Shiquan Liu,

Affiliation Department of Gastroenterology, The First Affiliated Hospital, Guangxi Medical University, Nanning, China
⨯
Jiean Huang

* E-mail: hjagxmu@163.com

Affiliation Department of Gastroenterology, The First Affiliated Hospital, Guangxi Medical University, Nanning, China
⨯

Knockdown of NIK and IKKβ-Binding Protein (NIBP) Reduces Colorectal Cancer Metastasis through Down-Regulation of the Canonical NF-κΒ Signaling Pathway and Suppression of MAPK Signaling Mediated through ERK and JNK

Mengbin Qin,
Jinxiu Zhang,
Chunyan Xu,
Peng Peng,
Lin Tan,
Shiquan Liu,
Jiean Huang

x

Published: January 26, 2017
https://doi.org/10.1371/journal.pone.0170595

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Colorectal cancer
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Transcription factors
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Metastasis
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Cancer treatment
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ERK signaling cascade
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Adenocarcinoma
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MAPK signaling cascades
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