Immunogenicity of Isogenic IgG in Aggregates and Immune Complexes

J. Benjamin St. Clair; Thiago Detanico; Katja Aviszus; Greg A. Kirchenbaum; Merry Christie; John F. Carpenter; Lawrence J. Wysocki

doi:10.1371/journal.pone.0170556

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Open Access

Peer-reviewed

Research Article

Immunogenicity of Isogenic IgG in Aggregates and Immune Complexes

J. Benjamin St. Clair,

Affiliations Department of Biomedical Research, National Jewish Health, Denver CO, United States of America, Medical Scientist Training Program, University of Colorado School of Medicine, Denver, Colorado, United States of America, Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, United States of America
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Thiago Detanico,

Affiliations Department of Biomedical Research, National Jewish Health, Denver CO, United States of America, Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, United States of America
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Katja Aviszus,

Affiliations Department of Biomedical Research, National Jewish Health, Denver CO, United States of America, Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, United States of America
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Greg A. Kirchenbaum,

Current address: Department of Infectious Disease, University of Georgia College of Veterinary Medicine, Athens, Georgia, United States of America

Affiliation Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, United States of America
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Merry Christie,

Current address: Office of Biotechnology Products, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America

Affiliation Department of Pharmaceutical Sciences, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America
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John F. Carpenter,

Affiliation Department of Pharmaceutical Sciences, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America
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Lawrence J. Wysocki

* E-mail: wysockil@njhealth.org

Current address: Department of Immunology, University of Colorado School of Medicine, Denver, Colorado, United States of America

Affiliation Department of Biomedical Research, National Jewish Health, Denver CO, United States of America

http://orcid.org/0000-0003-1463-4162

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Immunogenicity of Isogenic IgG in Aggregates and Immune Complexes

J. Benjamin St. Clair,
Thiago Detanico,
Katja Aviszus,
Greg A. Kirchenbaum,
Merry Christie,
John F. Carpenter,
Lawrence J. Wysocki

Published: January 23, 2017
https://doi.org/10.1371/journal.pone.0170556

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