Peptide Targeted by Human Antibodies Associated with HIV Vaccine-Associated Protection Assumes a Dynamic α-Helical Structure

Mohammed S. Aiyegbo; Evgeny Shmelkov; Lorenzo Dominguez; Michael Goger; Shibani Battacharya; Allan C. deCamp; Peter B. Gilbert; Phillip W. Berman; Timothy Cardozo

doi:10.1371/journal.pone.0170530

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Peer-reviewed

Research Article

Peptide Targeted by Human Antibodies Associated with HIV Vaccine-Associated Protection Assumes a Dynamic α-Helical Structure

Mohammed S. Aiyegbo ,

Contributed equally to this work with: Mohammed S. Aiyegbo, Evgeny Shmelkov

Affiliation Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America
⨯
Evgeny Shmelkov ,

Contributed equally to this work with: Mohammed S. Aiyegbo, Evgeny Shmelkov

Affiliation Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America
⨯
Lorenzo Dominguez,

Affiliation Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America
⨯
Michael Goger,

Affiliation The New York Structural Biology Center, New York, New York, United States of America
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Shibani Battacharya,

Affiliation The New York Structural Biology Center, New York, New York, United States of America
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Allan C. deCamp,

Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Peter B. Gilbert,

Affiliations Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Biostatistics, University of Washington, Seattle, Washington, United States of America
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Phillip W. Berman,

Affiliation Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America
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Timothy Cardozo

* E-mail: timothy.cardozo@nyumc.org

Affiliation Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America
⨯

Peptide Targeted by Human Antibodies Associated with HIV Vaccine-Associated Protection Assumes a Dynamic α-Helical Structure

Mohammed S. Aiyegbo,
Evgeny Shmelkov,
Lorenzo Dominguez,
Michael Goger,
Shibani Battacharya,
Allan C. deCamp,
Peter B. Gilbert,
Phillip W. Berman,
Timothy Cardozo

Published: January 20, 2017
https://doi.org/10.1371/journal.pone.0170530

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HIV vaccines
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HIV infections
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Protein structure prediction
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