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Open Access

Peer-reviewed

Research Article

The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis

Iva Machová,

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic
⨯
Martin Hubálek,

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic
⨯
Martin Lepšík,

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic
⨯
Lucie Bednárová,

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic
⨯
Markéta Pazderková,

Affiliations Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic, Institute of Physics, Faculty of Mathematics and Physics, Charles University in Prague, Prague, Czech Republic
⨯
Vladimír Kopecký Jr.,

Affiliation Institute of Physics, Faculty of Mathematics and Physics, Charles University in Prague, Prague, Czech Republic
⨯
Jan Snášel,

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic
⨯
Jiří Dostál,

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic
⨯
Iva Pichová

* E-mail: iva.pichova@uochb.cas.cz

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic
⨯

The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis

Iva Machová,
Martin Hubálek,
Martin Lepšík,
Lucie Bednárová,
Markéta Pazderková,
Vladimír Kopecký Jr.,
Jan Snášel,
Jiří Dostál,
Iva Pichová

x

Published: January 30, 2017
https://doi.org/10.1371/journal.pone.0170373

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Mycobacterium tuberculosis
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Cysteine
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Enzyme structure
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Circular dichroism spectroscopy
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Molecular dynamics
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Enzyme metabolism
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Raman spectroscopy
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Enzymes
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