CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells

Naser Jafari; Hyunju Kim; Rackhyun Park; Liqing Li; Minsu Jang; Andrew J. Morris; Junsoo Park; Cai Huang

doi:10.1371/journal.pone.0170327

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Peer-reviewed

Research Article

CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells

Naser Jafari ,

Contributed equally to this work with: Naser Jafari, Hyunju Kim

Affiliation Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Hyunju Kim ,

Contributed equally to this work with: Naser Jafari, Hyunju Kim

Affiliations Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea
⨯
Rackhyun Park,

Affiliations Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea
⨯
Liqing Li,

Affiliation Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Minsu Jang,

Affiliations Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea
⨯
Andrew J. Morris,

Affiliation Division of Cardiovascular Medicine, Department of Internal Medicine, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Junsoo Park ,

* E-mail: junsoo@yonsei.ac.kr (JP); cai-huang@uky.edu (CH)

Affiliations Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea

http://orcid.org/0000-0002-2355-6760

⨯
Cai Huang

* E-mail: junsoo@yonsei.ac.kr (JP); cai-huang@uky.edu (CH)

Affiliation Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America
⨯

CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells

Naser Jafari,
Hyunju Kim,
Rackhyun Park,
Liqing Li,
Minsu Jang,
Andrew J. Morris,
Junsoo Park,
Cai Huang

Published: January 18, 2017
https://doi.org/10.1371/journal.pone.0170327

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05 Aug 2017
09:23 GMT
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