Rheumatic Heart Disease and Myxomatous Degeneration: Differences and Similarities of Valve Damage Resulting from Autoimmune Reactions and Matrix Disorganization

• Carlo de Oliveira Martins ,

  ¶‡ These authors are first authors on this work.

  Affiliations Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil, Institute of Investigation in Immunology, National Institute for Science and Technology, University of São Paulo, São Paulo, São Paulo, Brazil

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• Lea Demarchi ,

  ¶‡ These authors are first authors on this work.

  Affiliation Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil

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• Frederico Moraes Ferreira,

  Affiliations Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil, Institute of Investigation in Immunology, National Institute for Science and Technology, University of São Paulo, São Paulo, São Paulo, Brazil

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• Pablo Maria Alberto Pomerantzeff,

  Affiliation Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil

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• Carlos Brandao,

  Affiliation Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil

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• Roney Orismar Sampaio,

  Affiliation Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil

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• Guilherme Sobreira Spina,

  Affiliation Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil

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• Jorge Kalil,

  Affiliations Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil, Institute of Investigation in Immunology, National Institute for Science and Technology, University of São Paulo, São Paulo, São Paulo, Brazil

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• Edecio Cunha-Neto,

  Affiliations Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil, Institute of Investigation in Immunology, National Institute for Science and Technology, University of São Paulo, São Paulo, São Paulo, Brazil

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• Luiza Guilherme

  * E-mail: luizagui@usp.br

  Affiliations Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, São Paulo, Brazil, Institute of Investigation in Immunology, National Institute for Science and Technology, University of São Paulo, São Paulo, São Paulo, Brazil

  http://orcid.org/0000-0003-0997-1498

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