Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß

Isaac Hurtado-Guerrero; Maria Jesús Pinto-Medel; Patricia Urbaneja; Jose Luis Rodriguez- Bada; Antonio León; Miguel Guerrero; Óscar Fernández; Laura Leyva; Begoña Oliver-Martos

doi:10.1371/journal.pone.0170031

Loading metrics

Open Access

Peer-reviewed

Research Article

Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß

Isaac Hurtado-Guerrero,

Affiliation Unidad de Gestión Clínica de Neurociencias, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain
⨯
Maria Jesús Pinto-Medel,

Affiliation Unidad de Gestión Clínica de Neurociencias, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain
⨯
Patricia Urbaneja,

Affiliation Unidad de Gestión Clínica de Neurociencias, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain
⨯
Jose Luis Rodriguez- Bada,

Affiliation Unidad de Gestión Clínica de Neurociencias, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain
⨯
Antonio León,

Affiliation Unidad de Gestión Clínica de Neurociencias, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain
⨯
Miguel Guerrero,

Affiliation Unidad de Gestión Clínica de Neurociencias, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain
⨯
Óscar Fernández,

Affiliation Unidad de Gestión Clínica de Neurociencias, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain
⨯
Laura Leyva ,

Contributed equally to this work with: Laura Leyva, Begoña Oliver-Martos

* E-mail: begoliver@gmail.com (BOM); leyvafer@gmail.com (LL)

Affiliation Unidad de Gestión Clínica de Neurociencias, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain
⨯
Begoña Oliver-Martos

Contributed equally to this work with: Laura Leyva, Begoña Oliver-Martos

* E-mail: begoliver@gmail.com (BOM); leyvafer@gmail.com (LL)

Affiliation Unidad de Gestión Clínica de Neurociencias, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain
⨯

Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß

Isaac Hurtado-Guerrero,
Maria Jesús Pinto-Medel,
Patricia Urbaneja,
Jose Luis Rodriguez- Bada,
Antonio León,
Miguel Guerrero,
Óscar Fernández,
Laura Leyva,
Begoña Oliver-Martos

Published: January 19, 2017
https://doi.org/10.1371/journal.pone.0170031

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Monocytes
Is the Subject Area "Monocytes" applicable to this article?

Thanks for your feedback.
JAK-STAT signaling cascade
Is the Subject Area "JAK-STAT signaling cascade" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Multiple sclerosis
Is the Subject Area "Multiple sclerosis" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Magnetic resonance imaging
Is the Subject Area "Magnetic resonance imaging" applicable to this article?

Thanks for your feedback.
Cytokine therapy
Is the Subject Area "Cytokine therapy" applicable to this article?

Thanks for your feedback.
Interferons
Is the Subject Area "Interferons" applicable to this article?

Thanks for your feedback.