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Open Access
Peer-reviewed
Research Article
A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate
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Alice C. O’Farrell ,
Contributed equally to this work with: Alice C. O’Farrell, Rhys Evans
Affiliation Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland
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Rhys Evans ,
Contributed equally to this work with: Alice C. O’Farrell, Rhys Evans
Affiliation Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland
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Johanna M. U. Silvola,
Affiliation Turku PET Centre, Turku University Hospital and Åbo Akademi University, Turku, Finland
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Ian S. Miller,
Affiliation Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland
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Emer Conroy,
Affiliation UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland
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Suzanne Hector,
Affiliations Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland, Roche Innovation Center Basel, F Hoffman La Roche, Basel, Switzerland
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Maurice Cary,
Affiliation Pathology Experts GmbH, Basel, Switzerland
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David W. Murray,
Affiliations Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland, Oncomark Ltd, Dublin, Ireland
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Monika A. Jarzabek,
Affiliations Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland, Roche Innovation Center Basel, F Hoffman La Roche, Basel, Switzerland
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Ashwini Maratha,
Affiliation Oncomark Ltd, Dublin, Ireland
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Marina Alamanou,
Affiliation Oncomark Ltd, Dublin, Ireland
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Girish Mallya Udupi,
Affiliation Oncomark Ltd, Dublin, Ireland
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Liam Shiels,
Affiliation Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland
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Celine Pallaud,
Affiliation Roche Innovation Center Basel, F Hoffman La Roche, Basel, Switzerland
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Antti Saraste,
Affiliations Turku PET Centre, Turku University Hospital and Åbo Akademi University, Turku, Finland, Heart Center, Turku University Hospital and Åbo Akademi University, Turku, Finland
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Heidi Liljenbäck,
Affiliation Turku PET Centre, Turku University Hospital and Åbo Akademi University, Turku, Finland
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Matti Jauhiainen,
Affiliation Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland
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Vesa Oikonen,
Affiliation Turku PET Centre, Turku University Hospital and Åbo Akademi University, Turku, Finland
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Axel Ducret,
Affiliation Roche Innovation Center Basel, F Hoffman La Roche, Basel, Switzerland
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Paul Cutler,
Affiliation Roche Innovation Center Basel, F Hoffman La Roche, Basel, Switzerland
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Fionnuala M. McAuliffe,
Affiliation UCD Obstetrics & Gynaecology, School of Medicine, University College, Dublin, National Maternity Hospital, Dublin, Ireland
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Jacques A. Rousseau,
Affiliation Université de Sherbrooke, Québec, Canada
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Roger Lecomte,
Affiliation Université de Sherbrooke, Québec, Canada
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Suzanne Gascon,
Affiliation Université de Sherbrooke, Québec, Canada
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Zoltan Arany,
Affiliation Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
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Bonnie Ky,
Affiliation Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
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Thomas Force,
Affiliation Vanderbilt University School of Medicine, Nashville, United States of America
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Juhani Knuuti,
Affiliation Turku PET Centre, Turku University Hospital and Åbo Akademi University, Turku, Finland
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William M. Gallagher,
Affiliations UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland, Oncomark Ltd, Dublin, Ireland
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Anne Roivainen,
Affiliations Turku PET Centre, Turku University Hospital and Åbo Akademi University, Turku, Finland, Turku Center for Disease Modeling, University of Turku, Turku, Finland
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Annette T. Byrne
* E-mail: annettebyrne@rcsi.ie
Affiliation Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland
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A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate
- Alice C. O’Farrell,
- Rhys Evans,
- Johanna M. U. Silvola,
- Ian S. Miller,
- Emer Conroy,
- Suzanne Hector,
- Maurice Cary,
- David W. Murray,
- Monika A. Jarzabek,
- Ashwini Maratha
- Published: January 27, 2017
- https://doi.org/10.1371/journal.pone.0169964