Splenic CD4⁺ T Cells in Progressive Visceral Leishmaniasis Show a Mixed Effector-Regulatory Phenotype and Impair Macrophage Effector Function through Inhibitory Receptor Expression

• Audrie A. Medina-Colorado,

  Affiliation Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

  http://orcid.org/0000-0002-4917-666X

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• Elvia Y. Osorio,

  Affiliation Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Omar A. Saldarriaga,

  Affiliation Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Bruno L. Travi,

  Affiliations Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, United States of America, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Fanping Kong,

  Affiliation Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Heidi Spratt,

  Affiliations Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Lynn Soong,

  Affiliations Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Peter C. Melby

  * E-mail: pcmelby@utmb.edu

  Affiliations Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, United States of America, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

  http://orcid.org/0000-0001-7320-7406

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