Lower Frequency of HLA-DRB1 Type 1 Diabetes Risk Alleles in Pediatric Patients with MODY

Inés Urrutia; Rosa Martínez; Tamara López-Euba; Teresa Velayos; Idoia Martínez de LaPiscina; José Ramón Bilbao; Itxaso Rica; Luis Castaño; on behalf of The Spanish Group for the Study of MODY and Type 1 diabetes

doi:10.1371/journal.pone.0169389

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Open Access

Peer-reviewed

Research Article

Lower Frequency of HLA-DRB1 Type 1 Diabetes Risk Alleles in Pediatric Patients with MODY

Inés Urrutia ,

Contributed equally to this work with: Inés Urrutia, Rosa Martínez

Affiliation BioCruces Health Research Institute, Cruces University Hospital, UPV-EHU, CIBERDEM, CIBERER, Barakaldo, Spain

http://orcid.org/0000-0001-5386-8776

⨯
Rosa Martínez ,

Contributed equally to this work with: Inés Urrutia, Rosa Martínez

Affiliation BioCruces Health Research Institute, Cruces University Hospital, UPV-EHU, CIBERDEM, CIBERER, Barakaldo, Spain
⨯
Tamara López-Euba,

Affiliation BioCruces Health Research Institute, Cruces University Hospital, UPV-EHU, CIBERDEM, CIBERER, Barakaldo, Spain
⨯
Teresa Velayos,

Affiliation BioCruces Health Research Institute, Cruces University Hospital, UPV-EHU, CIBERDEM, CIBERER, Barakaldo, Spain
⨯
Idoia Martínez de LaPiscina,

Affiliation BioCruces Health Research Institute, Cruces University Hospital, UPV-EHU, CIBERDEM, CIBERER, Barakaldo, Spain
⨯
José Ramón Bilbao,

Affiliation BioCruces Health Research Institute, Cruces University Hospital, UPV-EHU, CIBERDEM, CIBERER, Barakaldo, Spain
⨯
Itxaso Rica,

Affiliation BioCruces Health Research Institute, Cruces University Hospital, UPV-EHU, CIBERDEM, CIBERER, Barakaldo, Spain
⨯
Luis Castaño ,

* E-mail: lcastano@osakidetza.eus

Affiliation BioCruces Health Research Institute, Cruces University Hospital, UPV-EHU, CIBERDEM, CIBERER, Barakaldo, Spain
⨯
on behalf of The Spanish Group for the Study of MODY and Type 1 diabetes

¶Membership of The Spanish Group for the Study of MODY and Type 1 diabetes is provided after the Acknowledgments

Affiliation BioCruces Health Research Institute, Cruces University Hospital, UPV-EHU, CIBERDEM, CIBERER, Barakaldo, Spain
⨯

Lower Frequency of HLA-DRB1 Type 1 Diabetes Risk Alleles in Pediatric Patients with MODY

Inés Urrutia,
Rosa Martínez,
Tamara López-Euba,
Teresa Velayos,
Idoia Martínez de LaPiscina,
José Ramón Bilbao,
Itxaso Rica,
Luis Castaño,
on behalf of The Spanish Group for the Study of MODY and Type 1 diabetes

Published: January 4, 2017
https://doi.org/10.1371/journal.pone.0169389

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Diabetes mellitus
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Medical risk factors
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Autoantibodies
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Variant genotypes
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Human genetics
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Pediatrics
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Type 2 diabetes
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Genotyping
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