Effects of Direct Renin Blockade on Renal & Systemic Hemodynamics and on RAAS Activity, in Weight Excess and Hypertension: A Randomized Clinical Trial

• A. J. Kwakernaak ,

  * E-mail: a.j.kwakernaak@hotmail.nl

  Affiliation Department of Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, The Netherlands

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• L. C. Roksnoer,

  Affiliation Department of Medicine, Division of Vascular Medicine and Pharmacology, Erasmus Medical Center, Rotterdam, The Netherlands

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• H. J. Lambers Heerspink,

  Affiliation Department of Clinical Pharmacology, University of Groningen, University Medical Center Groningen, The Netherlands

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• I. van den Berg-Garrelds,

  Affiliation Department of Medicine, Division of Vascular Medicine and Pharmacology, Erasmus Medical Center, Rotterdam, The Netherlands

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• G. A. Lochorn,

  Affiliation General Practitioner Practice Gorecht, Hoogezand, The Netherlands

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• J. H. van Embden Andres,

  Affiliation General Practitioner Practice Boterdiep, Groningen, The Netherlands

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• M. A. Klijn,

  Affiliation General Practitioner Practice Boterdiep, Groningen, The Netherlands

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• H. Kobori,

  Affiliation Department of Pharmacology, Kagawa University, School of Medicine, Miki, Kita District, Kagawa, Japan

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• A. H. J. Danser,

  Affiliation Department of Medicine, Division of Vascular Medicine and Pharmacology, Erasmus Medical Center, Rotterdam, The Netherlands

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• G. D. Laverman,

  Affiliations Department of Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, The Netherlands, Department of Internal Medicine, Division of Nephrology, ZGT Hospital Almelo, Netherlands

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• G. J. Navis

  Affiliation Department of Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, The Netherlands

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