Generation of a Stable Transgenic Swine Model Expressing a Porcine Histone 2B-eGFP Fusion Protein for Cell Tracking and Chromosome Dynamics Studies

Renan B. Sper; Sehwon Koh; Xia Zhang; Sean Simpson; Bruce Collins; Jeff Sommer; Robert M. Petters; Ignacio Caballero; Jeff L. Platt; Jorge A. Piedrahita

doi:10.1371/journal.pone.0169242

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Open Access

Peer-reviewed

Research Article

Generation of a Stable Transgenic Swine Model Expressing a Porcine Histone 2B-eGFP Fusion Protein for Cell Tracking and Chromosome Dynamics Studies

Renan B. Sper ,

Contributed equally to this work with: Renan B. Sper, Sehwon Koh, Xia Zhang

Affiliations Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America, Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Sehwon Koh ,

Contributed equally to this work with: Renan B. Sper, Sehwon Koh, Xia Zhang

Current address: Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, United States of America.

Affiliation Department of Surgery and Microbiology and Immunology, University of Michigan Health System, Ann Arbor, Michigan, United States of America
⨯
Xia Zhang ,

Contributed equally to this work with: Renan B. Sper, Sehwon Koh, Xia Zhang

Affiliations Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America, Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States of America
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Sean Simpson,

Affiliations Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America, Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States of America
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Bruce Collins,

Affiliations Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America, Department of Animal Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, North Carolina, United States of America
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Jeff Sommer,

Affiliation Department of Animal Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, North Carolina, United States of America
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Robert M. Petters,

Affiliations Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America, Department of Animal Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Ignacio Caballero,

Current address: French National Institute for Agricultural Research (INRA), Nouzilly, France

Affiliation Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Jeff L. Platt,

Affiliation Department of Surgery and Microbiology and Immunology, University of Michigan Health System, Ann Arbor, Michigan, United States of America
⨯
Jorge A. Piedrahita

* E-mail: japiedra@ncsu.edu

Affiliations Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America, Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States of America

http://orcid.org/0000-0001-9751-3192

⨯

Generation of a Stable Transgenic Swine Model Expressing a Porcine Histone 2B-eGFP Fusion Protein for Cell Tracking and Chromosome Dynamics Studies

Renan B. Sper,
Sehwon Koh,
Xia Zhang,
Sean Simpson,
Bruce Collins,
Jeff Sommer,
Robert M. Petters,
Ignacio Caballero,
Jeff L. Platt,
Jorge A. Piedrahita

Published: January 12, 2017
https://doi.org/10.1371/journal.pone.0169242

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